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Bioprinting approaches in cardiac tissue engineering to reproduce blood-pumping heart function.
iScience
January 2025
Department of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), Pohang, South Korea.
The heart, with its complex structural and functional characteristics, plays a critical role in sustaining life by pumping blood throughout the entire body to supply nutrients and oxygen. Engineered heart tissues have been introduced to reproduce heart functions to understand the pathophysiological properties of the heart and to test and develop potential therapeutics. Although numerous studies have been conducted in various fields to increase the functionality of heart tissue to be similar to reality, there are still many difficulties in reproducing the blood-pumping function of the heart.
View Article and Find Full Text PDFRecent Developments in Ventricular Assist Device Therapy.
Rev Cardiovasc Med
January 2025
Center for Preclinical Surgical & Interventional Research, The Texas Heart Institute, Houston, TX 77030, USA.
The evolution of left ventricular assist devices (LVADs) from large, pulsatile systems to compact, continuous-flow pumps has significantly improved implantation outcomes and patient mobility. Minimally invasive surgical techniques have emerged that offer reduced morbidity and enhanced recovery for LVAD recipients. Innovations in wireless power transfer technologies aim to mitigate driveline-related complications, enhancing patient safety and quality of life.
View Article and Find Full Text PDFEndoscopic Combined Intrarenal Surgery for a Large Stone in a Rare Fused Supernumerary Kidney.
Cureus
December 2024
Urology, Hospital General Dr. Agustín O'Horán, Mérida, MEX.
A supernumerary kidney is a rare birth defect where an extra kidney is present. This extra kidney has its own separate outer covering, blood supply, and collection system. Normally, percutaneous nephrolithotomy (PCNL) is the treatment of choice for large kidney stones, but its ideal use for supernumerary kidneys is unknown.
View Article and Find Full Text PDFBioengineering strategies targeting angiogenesis: Innovative solutions for osteonecrosis of the femoral head.
J Tissue Eng
January 2025
Department of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong SAR, China.
Osteonecrosis of the femoral head (ONFH) is a prevalent orthopedic disorder characterized primarily by compromised blood supply. This vascular deficit results in cell apoptosis, trabecular bone loss, and structural collapse of the femoral head at late stage, significantly impairing joint function. While MRI is a highly effective tool for diagnosing ONFH in its early stages, challenges remain due to the limited availability and high cost of MRI, as well as the absence of routine MRI screening in asymptomatic patients.
View Article and Find Full Text PDFSuccessful management of Leydig Cell Tumor in a 65-year-Old patient: A rare case report.
Urol Case Rep
January 2025
Faculty member, Faculty of Medicine, Pathology Department, Damascus University, Damascus, Syrian Arab Republic.
Leydig cell tumors (LCTs) are rare testicular neoplasms, representing 1-3% of all testicular tumors. A 65-year-old male presented with a painless left scrotal mass. Ultrasound revealed a 61 × 53 × 35 mm tumor with heterogeneous echogenicity and abundant blood supply.
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