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Aim: To discuss inter-organisational collaboration in the context of the successful COVID-19 vaccination programme in North Central London (NCL).

Design: An action research study in 2023-2024.

Methods: Six action research cycles used mixed qualitative methods.

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Neuropeptides in the hypothalamus.

Vitam Horm

January 2025

Laboratory of Neuroanatomy of the Peptidergic Systems, Institute of Neurosciences of Castilla and León (INCYL), University of Salamanca, Salamanca, Spain; Grupo GIR USAL-BMD (Bases Moleculares del Desarrollo), University of Salamanca, Salamanca, Spain.

The hypothalamus is one of the most complex region in the central nervous system regarding neuroanatomy, neurochemical content, neuropeptide/classical neurotransmitter interactions, physiological actions, and pathophysiology. Hypothalamic neuropeptides have been involved in a large plethora of mechanisms related with obesity, anxiety, feeding, energy metabolism, defensive behavior, mood, and reproduction. The therapeutic potential of these findings is enormous but the physiological complexity occurring in the hypothalamus is huge due in part to the interactions between numerous neuropeptides as well as between neuropeptides and other neuroactive substances.

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Introduction: Homeobox genes are highly conserved and play critical roles in brain development. Recently we have found that mammals have an additional fragment of approximately 20 amino acids in Emx1 and a poly-(Ala)6-7 in Emx2, compared to other amniotes. It has been shown that Emx1 and Emx2 have synergistic actions in the brain development.

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Biomass, as a source of lignocellulose, can be valorized into carbon micro/nanofibers for adsorbing greenhouse gas (GHGs) emissions, especially CO. This article is derived from systematic evidence evaluation of published studies, presenting new, innovative, and systemic approaches to lignocellulose-based carbon micro/nanofiber studies. The review covers a general overview of carbon micro/nanofiber studies, mapping chronicles of the studies, carbon micro/nanofiber types for CO uptake, carbon micro/nanofibers fabrication and characterization, obtained carbonaceous material activation and performances, regulatory frameworks, and sustainability.

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Background: Bear bile powder (BBP), a unique animal-derived medicine with anti-inflammatory and antioxidant effects, is used in Shexiang Tongxin dropping pills (STDP), which is applied to treat cardiovascular diseases, including acute myocardial infarction (AMI). The efficacy and compatibility mechanisms of action of BBP in STDP against cardiovascular diseases remain unclear. This study aimed to investigate the compatibility effects of BBP in STDP in rats with AMI.

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