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Unresolved Complete Heart Block in a Patient Treated for Euthyroid Graves' Disease: A Diagnostic Dilemma.
Cureus
December 2024
Diabetes and Endocrinology, United Lincolnshire Hospital NHS Trust, Lincoln, GBR.
The cardiovascular implications of thyroid disease have been recognized as one of the most characteristic signs that result from the effect of thyroid hormone (TH). Both hyperthyroidism and hypothyroidism produce changes in cardiac contractility, myocardial oxygen consumption, cardiac output, blood pressure, and systemic vascular resistance. The bradyarrhythmias, including atrioventricular block and sick sinus syndrome, are exceedingly rare in hyperthyroidism.
View Article and Find Full Text PDFThermal and morphological properties of human erythrocytes from patients afflicted with type 1 diabetes mellitus.
Heliyon
January 2025
Department of Biophysics, Medical School, University of Pécs, Pécs, Hungary.
Red blood cells (RBC), are the most unique and abundant cell types. The diameter of RBCs is 7-8 μm. They have an essential role in transporting circulatory oxygen.
View Article and Find Full Text PDFPrevalence and determinants of metabolic syndrome among type2 diabetic patients using different diagnosis criteria in ethiopia: systematic review and meta-analysis.
BMC Public Health
January 2025
Department of Medical Nursing, School of Nursing, College of Medicine and Health Sciences, University of Gondar, P.O. BOX 196, Gondar City, Ethiopia.
Article Synopsis
- Metabolic syndrome is a growing public health issue globally, particularly linked to diseases like type 2 diabetes, and this study focuses on its prevalence among type 2 diabetic patients in Ethiopia.
- Researchers analyzed various studies to determine the pooled prevalence and factors contributing to metabolic syndrome, employing robust statistical methods to ensure accuracy and reliability of findings.
- The study found a significant prevalence of metabolic syndrome among type 2 diabetes patients in Ethiopia, with rates ranging from about 47% to over 59% depending on different diagnostic criteria, and it identified several risk factors associated with the condition.
High glucose induces renal tubular epithelial cell senescence by inhibiting autophagic flux.
Hum Cell
January 2025
Department of Nephrology, Zhong Da Hospital, Gulou District, No. 87, Dingjiaqiao, Zhongyangmen Street, Nanjing, 210009, Jiangsu, China.
Autophagy, a cellular degradation process involving the formation and clearance of autophagosomes, is mediated by autophagic proteins, such as microtubule-associated protein 1 light chain 3 (LC3) and sequestosome 1 (p62), and modulated by 3-methyladenine (3-MA) as well as chloroquine (CQ). Senescence, characterised by permanent cell cycle arrest, is marked by proteins such as cyclin-dependent kinase inhibitor 1 (p21) and tumour protein 53 (p53). This study aims to investigate the relationship between cell senescence and renal function in diabetic kidney disease (DKD) and the effect of autophagy on high-glucose-induced cell senescence.
View Article and Find Full Text PDFPrevalence and risk factors of stroke in patients with non-valvular atrial fibrillation: a case-control study.
World Neurosurg
January 2025
Department of Neurology, General Hospital of Ningxia Medical University, Yinchuan, 750000, Ningxia Hui Autonomous Region, China. Electronic address:
Objective: To analyze the prevalence and influencing factors of stroke in patients with non-valvular atrial fibrillation (SIPWNVAF), and to provide a reference basis for the prevention and control of stroke.
Methods: Data were obtained from the China National Stroke Screening Survey (CNSSS). From January 2016 to December 2023, a total of 15471 permanent residents aged ≥ 40 years in Yinchuan were screened.
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