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Diagnostic performance of whole brain volume perfusion CT in intra-axial brain tumors: preoperative classification accuracy and histopathologic correlation.
Eur J Radiol
December 2012
Department of Neuroradiology, Georg-August University, University Hospital of Goettingen, Robert-Koch Strasse 40, 37075 Goettingen, Germany.
Background: To evaluate the preoperative diagnostic power and classification accuracy of perfusion parameters derived from whole brain volume perfusion CT (VPCT) in patients with cerebral tumors.
Methods: Sixty-three patients (31 male, 32 female; mean age 55.6 ± 13.
[Extensive squamous papillomatosis of the oesophagus with malignant transformation of squamous epithelium].
Z Gastroenterol
November 2011
Gastroenterologie, Dr. Horst-Schmidt-Kliniken.
While small solitary oesophageal papillomas are uncommon findings that are occasionally identified on routine upper endoscopies, extensive oesophageal papillomatosis is an extremely rare condition with only 9 cases reported in the English literature. We report the case of a 72-year-old woman who was referred for progressive dysphagia for solid food and clinical signs for a reflux disease. Upper endoscopy demonstrated bizarre villous alterations of the mucosa covering the oesophagus subtotally and a suspicious area within these alterations.
View Article and Find Full Text PDFFull genome sequence analysis of parechoviruses from Brazil reveals geographical patterns in the evolution of non-structural genes and intratypic recombination in the capsid region.
J Gen Virol
March 2011
Research Laboratory for Infectious Diseases, Hospital Professor Edgar Santos, Federal University of Bahia, Salvador, Bahia, Brazil.
Due to high genome plasticity, the evolutionary fate and geographical history of picornaviruses is hard to follow. Here, we determined the complete coding sequences of eight human parechoviruses (HPeV) of types 1, 5 and 6 directly from clinical samples from Brazil. The capsid genes of these strains were not remarkably different from European, North American and Japanese HPeV.
View Article and Find Full Text PDFHow harmful is contralateral testicular biopsy?--an analysis of serial imaging studies and a prospective evaluation of surgical complications.
Eur Urol
October 2005
Urologische Abteilung, Albertinen-Krankenhaus, Suentelstrasse 11a, D - 22 457 Hamburg, Germany.
Objective: Testicular biopsy has recently gained a role in early detection of testicular cancer. However, its use is still limited mainly because of the fear of untoward consequences. There is a paucity of data regarding unfavourable effects of testicular biopsy.
View Article and Find Full Text PDFMethylene blue-aided chromoendoscopy for the detection of intraepithelial neoplasia and colon cancer in ulcerative colitis.
Gastroenterology
April 2003
I. Medical Clinic, Johannes Gutenberg University of Mainz, Mainz, Germany.
Background & Aims: Timely diagnosis of intraepithelial neoplasias (IN) and colitis-associated colon carcinomas (CRC) is crucially important for the treatment of ulcerative colitis (UC). We performed a randomized, controlled trial to test whether chromoendoscopy (CE) might facilitate early detection of IN and CRC in UC.
Methods: A total of 263 patients with long-standing UC (>or=8 years) were screened for potential inclusion in the study, 165 of whom were randomized at a 1:1 ratio to undergo conventional colonoscopy or colonoscopy with CE using 0.
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