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Right ventricle toxicity in cancer treatment: a focused review on cardiac imaging.
Future Cardiol
September 2023
Professor of Cardiology, Echocardiologist, Cardio-oncologist, Cardio-oncology Research Center, Shaheed Rajaie Cardiovascular Medical & Research Center, Iran University of Medical Science, Tehran, 1995614331, Iran.
The right ventricle (RV) remains the 'forgotten chamber' in the clinical assessment of cancer therapy-related cardiac dysfunction (CTRCD). We aimed to review the role that various cardiac imaging modalities play in RV assessment as part of the integrative management of patients undergoing cancer therapy. RV assessment remains challenging by traditional 2D echocardiography.
View Article and Find Full Text PDF[A critical analysis of ejection fraction].
Rev Med Chil
February 2022
Dept. Emergency Medicine, Drexel University College of Medicine, Philadelphia, PA, USA.
Ejection fraction (EF) is defined by the ratio of end-systolic volume (ESV) and end-diastolic volume (EDV). The resulting fraction is a dimensionless number whose interpretation is ambiguous and most likely misleading. Despite this limitation, EF is widely accepted as a clinical marker of cardiac function.
View Article and Find Full Text PDFDiagnostic value of echocardiography on detecting the various types of anomalous origin of the left coronary artery from the pulmonary artery.
J Thorac Dis
March 2020
Department of Cardiology, Xinhua Hospital Affiliated with the School of Medicine, Shanghai Jiao Tong University, Shanghai 200092, China.
Background: To assess the diagnostic value of echocardiography in detecting the various types of anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA).
Methods: A total of 30 patients with an established diagnosis of ALCAPA were retrospectively analyzed, and classified into infant- (n=20) and adult-type (n=10) groups according to the age of symptom manifestation and the mode of presentation. All patients underwent echocardiography examination.
TERT assists GDF11 to rejuvenate senescent VEGFR2/CD133 cells in elderly patients with myocardial infarction.
Lab Invest
November 2019
Department of Cardiology, Yangpu Hospital, Tongji University School of Medicine, 450 Tengyue Road, 200090, Shanghai, PR China.
Growth differentiation factor 11 (GDF11) is a transforming growth factor β superfamily member with a controversial role in rejuvenating old stem cells after acute injury in the elderly population. This study aimed to evaluate the effects of telomerase reverse transcriptase (TERT) on GDF11-mediated rejuvenation of senescent late-outgrowth endothelial progenitor cells (EPCs), defined as VEGFR2/CD133 cells, in elderly patients with acute myocardial infarction (AMI). We compared the quantity and capabilities of VEGFR2/CD133 cells from old (>60 years), middle-aged (45-60 years), and young (<45 years) AMI patients.
View Article and Find Full Text PDFCardiovascular imaging approach in pre and postoperative tetralogy of Fallot.
BMC Cardiovasc Disord
January 2019
Mid-German Heart Center, Department of Internal Medicine III (KIM-III), Division of Cardiology, Angiology and Intensive Medical Care, University Hospital Halle, Martin-Luther-University Halle, Ernst-Grube-Strasse 40, D-06120, Halle (Saale), Germany.
Advances in the medical and surgical management of Tetralogy of Fallot have led to marked increase of the number and age of survivors. Imaging in patients with Tetralogy of Fallot plays a crucial role in the diagnosis and follow up, and essentially guides management and intervention in this entity. This study systematically reviews the imaging modalities used in patients with Tetralogy of Fallot in the evaluation of preoperative and postoperative anatomic and hemodynamic lesions, as well as disease progression in this diagnosis.
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