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Different Types of Co-Infection by Contagious Ecthyma Virus, Enteropathogenic , , Ecto- and Endo-Parasites in Four Young Alpine Ibex ().
Animals (Basel)
December 2024
Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Regione Amerique 7G, 11020 Quart, AO, Italy.
The research aimed to investigate the perinatal pathology of Alpine ibex () through the study of four young subjects (at the age of 3 to 4 months) found dead in Valle d'Aosta, a region of northwestern Italy. The carcasses were submitted to necropsy followed by an examination of ecto- and endoparasites (ECP and ENP); samples from the gross lesions (in summary, cutaneous papilloma and crusts, ocular discharge, lobular haemorrhagic areas in the lungs, catarrhal-haemorrhagic enterocolitis) were analysed by bacteriological, histopathological, and biomolecular methods to define the etiological agent. The subjects, with various co-infection patterns, were affected by contagious ecthyma virus (ORFV) (agent of a highly diffusive pustular dermatitis transmissible to small ruminants and humans), Enteropathogenic (EPEC) (major etiological agent of infantile diarrhoea especially in developing countries), (MC) (cause of an ocular infection common to goats and sheep), various ECP (ticks and keds) and ENP (lung and intestinal nematodes, and coccidia).
View Article and Find Full Text PDFMpox (Monkeypox) On Board a Naval Warship.
Mil Med
December 2024
Division of Infectious Diseases, Johns Hopkins University, Baltimore, MD 21218, USA.
We report a case of mpox in an active duty male on board a naval warship, who presented with a chancre-like penile lesion and ulcerating lymphadenopathy in the setting of a nonreactive treponemal test. Despite empirical therapy for sexually transmitted infections, he developed a fever and a generalized pustular rash. The patient was placed in isolation, and contact tracing was performed.
View Article and Find Full Text PDFMonkeypox in Pakistan-First case report.
J Pak Med Assoc
October 2024
Department of Infectious Diseases, Pakistan Institute of Medical Sciences, Islamabad, Pakistan.
Article Synopsis
- - Monkeypox (mpox) is a rare viral infection caused by poxvirus, characterized by symptoms like fever, headaches, muscle aches, and a distinct rash.
- - There is no specific treatment for monkeypox, and available antiviral drugs and vaccines are limited; strict precautions are crucial to prevent its spread.
- - A case of a 41-year-old male with symptoms after traveling to Saudi Arabia highlights the need for medical professionals to remain vigilant, as no cases had been reported in Pakistan as of April 17, 2023.
Factors Affecting Treatment Persistence in Japanese Patients with Psoriasis Prescribed Biologics: A Real-World Study Using an Insurance Claim Database.
Dermatol Ther (Heidelb)
November 2024
Department of Dermatology, Nippon Medical School, Tokyo, Japan.
Article Synopsis
- * The study found that infliximab had the longest median treatment duration at 33.6 months, while brodalumab had the shortest at 9.7 months, with 1-year treatment survival rates being highest for guselkumab (83%) and lowest for brodalumab (45%).
- * Key factors influencing treatment persistence included male sex and specific psoriasis diagnostic codes, with bio-experienced patients showing slightly longer treatment lengths compared to bio-naïve patients.
Chronic Recurrent Multifocal Osteomyelitis Involving the Spine, Sternum, and Lower Extremities: A Case Report.
Pediatrics
October 2024
Department of Allergy, Immunology, and Rheumatology, University of Florida, Gainesville.
Article Synopsis
- - Chronic recurrent multifocal osteomyelitis (CRMO) is a nonbacterial bone disease in children that can be mistaken for infections or tumors, making early diagnosis and treatment crucial
- - A 10-year-old boy experienced pain and swelling in his ankle; initial tests were inconclusive, but four years later, he showed similar symptoms, leading to further imaging and biopsies that confirmed CRMO
- - The boy was treated with medications like celecoxib and infliximab, resulting in improved symptoms and remission over two years, although he developed a skin condition called palmoplantar pustular psoriasis that is often associated with CRMO
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