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Primary Ovarian Angiosarcoma: Diagnostic Challenges and Conundrums.
Discoveries (Craiova)
December 2024
Department of Oncopathology Homi Bhabha Cancer Hospital (HBCH) and Mahamana Pandit Madan Mohan Malviya Cancer Centre (MPMMCC), Tata Memorial Centre, Homi Bhabha National Institute (HBNI), Varanasi, India.
Angiosarcoma is an extremely uncommon mesenchymal neoplasm overall and moreso in female genital organs such as the ovary. Diagnosing primary ovarian angiosarcoma remains challenging on clinical grounds due to the absence of specific clinical symptoms as well as on histopathological analysis especially in poorly differentiated subtypes due to non-specific and overlapping morphologic features. Misdiagnosis in such scenarios can be devastating as this tumor is clinically very aggressive.
View Article and Find Full Text PDFMR Imaging of Typical Ovarian Hemangioma: A Case Report.
Curr Med Imaging
August 2024
Department of Medical Imaging, Chongqing University Fuling Hospital, Chongqing, China.
Article Synopsis
- Ovarian hemangioma is a rare tumor, with about 60 cases reported, but only around 10 investigated using MRI and ultrasound, often found by chance during autopsies or surgeries.
- A case study details a 51-year-old woman with an asymptomatic ovarian hemangioma, discovered through a raised CA125 level and MRI, which showed a cystic solid mass in the left ovary.
- The conclusion highlights that the MRI features of ovarian hemangiomas resemble those of liver hemangiomas, underlining the need for awareness of these radiological traits for better diagnosis and treatment.
Angiosarcoma of the ovary treated with polyadenosine ribose polymerase Inhibition, a case report and review of the literature.
Gynecol Oncol Rep
October 2023
Division Gynecologic Oncology, Department of Obstetrics, Gynecology and Women's Health, University of Minnesota, Minneapolis, MN 55455, United States.
•Primary angiosarcoma of the ovary historically has no standard treatment due to its rarity, and outcomes have been variable.•Olaparib may represent a viable treatment option for primary angiosarcoma of the ovary with a somatic BRCA mutation.•Next-generation sequencing may play an important component in treatment of very rare cancers to guide new or uncommon therapies.
View Article and Find Full Text PDFPrimary ovarian angiosarcoma: Two case reports and review of literature.
World J Clin Cases
July 2023
Department of Pathology, Peking University People's Hospital, Beijing 100044, China.
Background: Angiosarcoma (AS) is a rare and highly aggressive soft tissue disease that most commonly arises in deep soft tissues. There are only a few reported cases of AS involving the ovary and even fewer reports of the underlying molecular abnormalities. Here, we briefly review two cases of primary ovarian AS (oAS) with specific molecular events and immune checkpoints.
View Article and Find Full Text PDFClinical and ultrasonographic findings of ovarian tumours in bitches: A retrospective study.
Theriogenology
October 2023
Department of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126, Perugia, Italy.
A retrospective study was carried out to investigate incidence, clinical signs and ultrasonographic findings of ovarian tumours in a population of dogs referred to the Veterinary Teaching Hospital of the University of Perugia (Italy) and Anicura Tyrus Veterinary Clinic (Terni, Italy). The period of study ranged from January 2005 to December 2021. A total of 1910 dogs were affected by neoplasia but only 35 of them (1.
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