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enteritis associated with bacteremia, spondylodiscitis, and late CIED-related endocarditis, a case report.

Heliyon

January 2024

Service de Maladies Infectieuses et Tropicales, Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, Université Paris-Saclay, 78 avenue du General Leclerc 92470 Le Kremlin-Bicêtre, France.

Campylobacter sp. is widely considered a leading causative agent of bacterial food-borne gastrointestinal illness. Discitis and endocarditis caused by spp.

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A systematic review of neglected tropical diseases (NTDs) in Myanmar.

PLoS Negl Trop Dis

November 2023

Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom.

Background: Neglected tropical diseases (NTDs) affect most impoverished communities in developing countries, like Myanmar in Southeast Asia. NTDs have been understudied and underreported in Myanmar.

Methods: A systematic review of published and grey literature (1900-2023) on neglected tropical diseases (NTDs) in Myanmar was conducted.

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Genetic background of neomycin resistance in clinical isolated from Danish pig farms.

Appl Environ Microbiol

October 2023

Department of Veterinary and Animal Sciences, Section for Veterinary Clinical Microbiology, University of Copenhagen, Frederiksberg C, Denmark.

Neomycin is the first-choice antibiotic for the treatment of porcine enteritis caused by enterotoxigenic . Resistance to this aminoglycoside is on the rise after the increased use of neomycin due to the ban on zinc oxide. We identified the neomycin resistance determinants and plasmid contents in a historical collection of 128 neomycin-resistant clinical isolates from Danish pig farms.

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Article Synopsis
  • Escherichia coli (E. coli) shows inherent resistance to macrolides but can gain additional resistance through gene transfer, which is a concern in pig veterinary medicine.
  • A study investigated macrolide resistance in 324 E. coli isolates from pigs and tested the effectiveness of peptidomimetics as enhancers of macrolide efficacy against neomycin-resistant strains.
  • Results indicated that combining macrolides with peptidomimetics significantly reduced the minimum inhibitory concentrations (MICs) of the antibiotics, suggesting a potential method to improve treatment for E. coli infections in pigs.
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Raoultella planticola is a Gram-negative, aerobic, non-motile bacterium, abundant in the environment, but rarely associated with pathology in humans. Notably, few urinary tract infections caused by R. planticola have been reported.

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