Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Research note: Effect of a biotechnologically produced Pleurotus sapidus mycelium on expression of genes involved in protein synthesis and degradation in breast muscle of broilers.
Poult Sci
December 2024
Institute of Animal Nutrition and Nutrition Physiology, Justus Liebig University Giessen, Giessen, Germany; Center for Sustainable Food Systems, Justus Liebig University Giessen, Giessen, Germany. Electronic address:
Recently, feeding a fungal mycelium from Pleurotus sapidus was found to reduce relative breast muscle weight of broilers. The present study tested the hypothesis that dietary inclusion of P. sapidus mycelium modulates the expression of genes involved in protein anabolic and protein catabolic pathways in breast muscle of broilers.
View Article and Find Full Text PDFWhole-Body and Forearm Muscle Protein Metabolism in Patients With Acromegaly Before and After Treatment.
J Clin Endocrinol Metab
August 2023
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus 8200, Denmark.
Article Synopsis
- Active acromegaly leads to increased lean body mass due to enhanced protein synthesis, but the underlying mechanisms are not fully understood.
- The study involved analyzing 18 acromegaly patients before and after treatment, using various methods to measure protein kinetics and body composition.
- Results showed a significant decrease in lean body mass and energy expenditure after disease control, while protein breakdown and synthesis rates changed, suggesting that acromegaly creates a unique state with altered protein dynamics that still requires further investigation.
Depressed Protein Synthesis and Anabolic Signaling Potentiate ACL Tear-Resultant Quadriceps Atrophy.
Am J Sports Med
January 2023
Center for Muscle Biology, University of Kentucky, Lexington, Kentucky, USA.
Background: Anterior cruciate ligament (ACL) tear (ACLT) leads to protracted quadriceps muscle atrophy. Protein turnover largely dictates muscle size and is highly responsive to injury and loading. Regulation of quadriceps molecular protein synthetic machinery after ACLT has largely been unexplored, limiting development of targeted therapies.
View Article and Find Full Text PDFmiR-3960 from Mesenchymal Stem Cell-Derived Extracellular Vesicles Inactivates SDC1/Wnt/-Catenin Axis to Relieve Chondrocyte Injury in Osteoarthritis by Targeting PHLDA2.
Stem Cells Int
August 2022
Department of Orthopedic Trauma, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
Osteoarthritis (OA) is a serious disease of the articular cartilage characterized by excessive inflammation. Lately, mesenchymal stem cell- (MSC-) derived extracellular vesicles (EVs) have been proposed as a novel strategy for the treatment of OA. We aimed to investigate the effects of EV-encapsulated miR-3960 derived from MSCs on chondrocyte injury in OA.
View Article and Find Full Text PDFAcute effects of prior dietary fat ingestion on postprandial metabolic responses to protein and carbohydrate co-ingestion in overweight and obese men: A randomised crossover trial.
Clin Nutr
August 2022
MRC Versus Arthritis Centre for Musculoskeletal Ageing Research, School of Life Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, United Kingdom. Electronic address:
Background: Obesity and insulin resistance are associated with an impaired sensitivity to anabolic stimuli such as dietary protein (anabolic resistance). Omega-3 polyunsaturated fatty acids (n-3 PUFA) may be protective against the deleterious effects of saturated fatty acids (SFA) on insulin resistance. However, the contribution of excess fat consumption to anabolic and insulin resistance and the interaction between SFA and n-3 PUFA is not well studied.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!