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Laser Synthesis of Platinum Single-Atom Catalysts for Hydrogen Evolution Reaction.
Nanomaterials (Basel)
January 2025
Department of Materials, School of Natural Science, The University of Manchester, Oxford Road, Manchester M13 9PL, UK.
Platinum (Pt)-based heterogeneous catalysts show excellent performance for the electrocatalytic hydrogen evolution reaction (HER); however, the high cost and earth paucity of Pt means that efforts are being directed to reducing Pt usage, whilst maximizing catalytic efficiency. In this work, a two-step laser annealing process was employed to synthesize Pt single-atom catalysts (SACs) on a MOF-derived carbon substrate. The laser irradiation of a metal-organic framework (MOF) film (ZIF67@ZIF8 composite) by rapid scanning of a ns pulsed infrared (IR; 1064 nm) laser across the freeze-dried MOF resulted in a metal-loaded graphitized film.
View Article and Find Full Text PDFA Systematic Review of Challenges and Opportunities in the Implementation of Managed Entry Agreements for Advanced Therapy Medicinal Products.
Clin Ther
December 2024
Department of Epidemiology & Health Economics, Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands. Electronic address:
Purpose: Managed Entry Agreements (MEAs) are agreements between firms and competent authorities for pricing and reimbursement, designed to enable coverage of new medicines while managing uncertainties around their financial impact or performance. Although these agreements can facilitate patient access, their complexity and costs seem to dampen enthusiasm for implementation. Nevertheless, MEAs remain a potential route, particularly for high-cost drugs with uncertain value claims.
View Article and Find Full Text PDFUsing Large Language Models to Extract Core Injury Information From Emergency Department Notes.
J Korean Med Sci
December 2024
Laboratory of Emergency Medical Services, Seoul National University Hospital Biomedical Research Institute, Seoul, Korea.
Background: Injuries pose a significant global health challenge due to their high incidence and mortality rates. Although injury surveillance is essential for prevention, it is resource-intensive. This study aimed to develop and validate locally deployable large language models (LLMs) to extract core injury-related information from Emergency Department (ED) clinical notes.
View Article and Find Full Text PDFExploring the dual role of anti-nutritional factors in soybeans: a comprehensive analysis of health risks and benefits.
Crit Rev Food Sci Nutr
November 2024
Guelph Food Research Centre, Agriculture and Agri-Food Canada, Guelph, Canada.
Soybeans (Glycine max [L.] Merr.) are a globally significant crop, valued for their high protein content and nutritional versatility.
View Article and Find Full Text PDFDesigning orthopaedic seat cushion made of rattan using quality function deployment approach.
J Clin Orthop Trauma
November 2024
Faculty of Health and Life Science. INTI International University, Nilai, Malaysia.
Using ergonomic orthopaedic chairs can address spinal issues, particularly HNP, due to their flexible and elastic properties. By achieving optimal ergonomic design, various positive aspects can be achieved, such as increasing work quality productivity and reducing the cost of injuries or accidents. This research demonstrates diverse product design approaches to enhance posture health ergonomics, address specific musculoskeletal disorder issues, and consider local needs and available materials.
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