Heterologous radioimmunoassays (RIAs) for the mammalian prodynorphin end products, alpha-neo-endorphin, dynorphin A(1-17), dynorphin A(1-8), and dynorphin B(1-13) were used to screen brain extracts obtained from representatives of the major surviving orders of reptiles: Chelonia (Pseudemys scripta), Squamata (Anolis carolinensis), and Crocodylia (Alligator mississippiensis). Methanol/acid extracts of whole brains obtained from each species were separately fractionated by gel filtration chromatography and reversed-phase HPLC. In all three species, an immunoreactive form of alpha-neo-endorphin was detected with the same retention time as synthetic mammalian alpha-neo-endorphin following reversed-phase HPLC analysis. In all three species, reversed-phase HPLC analysis revealed a novel form of dynorphin B(1-13)-related immunoreactivity. With the available immunological probes, dynorphin A products were only detected in the Anolis brain extracts. Both dynorphin A(1-17) and dynorphin A(1-8) were detected in this species.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/0196-9781(92)90072-b | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Diagonal loading common spatial patterns with Pearson correlation coefficient based feature selection for efficient motor imagery classification.
Comput Methods Biomech Biomed Engin
January 2025
Department of Electronics and Electrical Communications, Faculty of Electronic Engineering, Menoufia University, Menouf, Egypt.
The conversion of a person's intentions into device commands through the use of brain-computer interface (BCI) is a feasible communication method for individuals with nervous system disorders. While common spatial pattern (CSP) is commonly used for feature extraction in BCIs, it has limitations. It is known for its susceptibility to noise and tendency to overfit.
View Article and Find Full Text PDFThe Efficacy of Repetitive Transorbital Alternating Current Stimulation (rtACS) in Patients With Optic Nerve Damage: A Systematic Review and Meta-Analysis.
Cureus
December 2024
Department of Ophthalmology, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Jeddah, SAU.
Optic nerve disorders significantly contribute to visual impairment with irreversible visual deficits. Current treatments have limited efficacy in resolving chronic visual deficits, necessitating novel therapeutic strategies. Neurorehabilitation techniques, including repetitive transorbital alternating current stimulation (rtACS), have emerged as promising approaches to restore lost visual function through the ability to modulate brain activity.
View Article and Find Full Text PDFThe role of conscious attention in auditory statistical learning: Evidence from patients with impaired consciousness.
iScience
January 2025
Cognitive Neuroimaging Unit U992, CNRS, INSERM, CEA, DRF/Institut Joliot, Université Paris-Saclay, NeuroSpin Center, 91191 Gif/Yvette, France.
The need for attention to enable statistical learning is debated. Testing individuals with impaired consciousness offers valuable insight, but very few studies have been conducted due to the difficulties inherent in such studies. Here, we examined the ability of patients with varying levels of disorders of consciousness (DOC) to extract statistical regularities from an artificial language composed of randomly concatenated pseudowords by measuring frequency tagging in EEG.
View Article and Find Full Text PDFArtificial intelligent based control strategy for reach and grasp of multi-objects using brain-controlled robotic arm system.
Network
January 2025
Department of Electrical and Electronics Engineering, University College of Engineering Thirukkuvalai - A Constituent College of Anna University, Thirukkuvalai, Tamil Nadu, India.
Brain-controlled robotic arm systems are designed to provide a method of communication and control for individuals with limited mobility or communication abilities. These systems can be beneficial for people who have suffered from a spinal cord injury, stroke, or neurological disease that affects their motor abilities. The ability of a person to control a robotic arm to reach and grasp multiple objects using their brain signals.
View Article and Find Full Text PDFThe pulsatile brain, pulse pressure, cognition, and antihypertensive treatments in older adults: a functional NIRS study.
J Hum Hypertens
January 2025
Research Centre, Montreal Heart Institute, Montreal, QC, Canada.
Age-related arterial stiffness increases pulsatility that reaches the cerebral microcirculation, compromises cerebrovascular health and lead to cognitive decline. The presence of cardiovascular risk factors (CVRFs) such as high blood pressure can exacerbate this effect. Despite extensive research on the impact of antihypertensive treatments on reducing arterial stiffness, little is known about the impact of antihypertensive treatments on pulsatility in cerebral microcirculation.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!