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Prevalence of and Fluoroquinolones Resistant Isolates: A Systematic Review and Meta-Analysis.
Vector Borne Zoonotic Dis
January 2024
Department of Bacteriology, Pasteur Institute of Iran, Tehran, Iran.
Article Synopsis
- Brucellosis affects both animals and humans globally, but treating it with antibiotics, particularly fluoroquinolones, is complex due to issues like relapse and resistance.
- Fluoroquinolones show significant benefits, including effectiveness against intracellular bacteria, low toxicity to kidneys, and no need for drug-level monitoring, which may help prevent disease recurrence.
- A systematic review of 47 studies revealed low resistance rates to several fluoroquinolones used against brucellosis, highlighting their potential as alternative treatments for patients facing complications from other therapies.
Genomic Characterization of Salmonella enterica Resistant to Cephalosporin, Quinolones, And Macrolides.
Curr Microbiol
September 2023
Department of Biotechnology, Middle East Technical University, Ankara, Türkiye.
Salmonella enterica subsp. enterica (Salmonella), one of the most common causes of bacterial foodborne infections, causes salmonellosis, which is usually self-limiting. However, immunocompromised individuals and children often require antimicrobial therapy.
View Article and Find Full Text PDF[Investigation of Azithromycin Minimum Inhibitory Concentration Values and Carbapenem Resistance in Salmonella and Shigella Clinical Isolates].
Mikrobiyol Bul
October 2021
Adnan Menderes University Faculty of Medicine, Department of Medical Microbiology, Aydın, Turkey.
Increasing resistance to first-line antibiotics used in the treatment of infections caused by Salmonella and Shigella species is emerging. Azithromycin presents a good alternative treatment option for Salmonella and Shigella infections. However, there are limited data regarding the susceptibility of azithromycin in Turkey.
View Article and Find Full Text PDFEmergence of resistance to fluoroquinolones among gram positive and gram negative clinical isolates.
Pak J Pharm Sci
October 2012
Jinnah Medical and Dental College, Karachi, Pakistan.
Fluoroquinolones are broad-spectrum antibiotics that are considered as first line drugs to treat infectious diseases. In order to find out useful fluoroquinolones, the antibiotic resistance of fluoroquinolones, namely, ofloxacin (OFL), ciprofloxacin (CIP), norfloxacin (NRF), enoxacin (ENX), pefloxacin (PFL) and levofloxacin (LVF) was investigated against ninety five clinical isolates that includes Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumoniae and Proteus mirabilis. In vitro activity of these isolates was carried out by agar dilution method.
View Article and Find Full Text PDFPresent possibilities of Q fever therapy.
Klin Mikrobiol Infekc Lek
February 2006
Department of Epidemiology, Medical Faculty of P.J.Safárik University Kosice, Slovak republic.
The first-line therapy for acute Q fever is 14 to 21 days of doxycycline, or fluoroquinolones such as ofloxacin or pefloxacin. Clarithromycin is a potential effective alternative. Chronic Q fever, especially endocarditis, requires treatment for at least 18 months, with the preferred combination of doxycycline and hydroxychloroquine.
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