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Morphological and genetic diversity assessment of cultivated Thymus satureioides (endemic species) of Morocco.
J Genet Eng Biotechnol
March 2025
National Institute of Agricultural Research (INRA), Regional Center of Agricultural Research Rabat, Biotechnology Unit, Rabat 10000 Morocco.
Thymus satureioides is an endemic and medicinal plant of Morocco, widely distributed in the arid and semiarid habitats. Communally used in traditional medicine. In the current study, twelve Inter-Simple Sequence Repeats (ISSR) primers combined with 11 agro-morphological traits were applied to evaluate 60 accessions of T.
View Article and Find Full Text PDFPharmacokinetics of the systemic application of hyaluronic acid for joint arthritis treatment.
Int J Biol Macromol
March 2025
Institute of Biophysics of the Czech Academy of Sciences, Brno, Czech Republic; International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic. Electronic address:
Frequent degenerative joint diseases, known as arthritis, are characterized by joint inflammation and cartilage breakdown. Various arthritis types are traditionally managed with intra-articular injections of hyaluronan or its derivatives. However, intravenous administration of hyaluronan is emerging as a vital alternative, particularly because intra-articular injections can be challenging for clinicians when targeting small or swollen joints.
View Article and Find Full Text PDFBiological evaluation of a new highly sensitive and selective fluorescent probe for hypochlorous acid and its imaging application in cell and zebrafish.
Bioorg Chem
March 2025
Biology Institute, Bioengineering Department, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China. Electronic address:
Hypochlorous acid is one of the most widely distributed reactive oxygen species in vivo. It is usually used as a signal molecule to participate in various life activities such as immunity and metabolism, and plays a notable role in maintaining homeostasis. When hypochlorous acid level is abnormal in the body, it will lead to a variety of diseases, such as Parkinson's disease, Alzheimer's disease, atherosclerosis and cancer.
View Article and Find Full Text PDFModeling Charge Collection in Silicon Pixel Detectors for Proton Therapy Applications.
Biomed Phys Eng Express
March 2025
Department of Physics and Technology, University of Bergen, Allégaten 55, Bergen, Hordaland, 5007, NORWAY.
Monolithic active pixel sensors are used for charged particle tracking in many applications, from medical physics to astrophysics. The Bergen pCT collaboration designed a sampling calorimeter for proton computed tomography, based entirely on the ALICE PIxel DEtector (ALPIDE). The same telescope can be used for in-situ range verification in particle therapy.
View Article and Find Full Text PDFRevealed Preferential Short-Range Anion Ordering in Disordered RbMOF (M = Nb, Ta) Pyrochlore-Type Oxyfluorides.
Inorg Chem
March 2025
Institut des Molécules et Matériaux du Mans (IMMM)─UMR 6283 CNRS, Le Mans Université, Avenue Olivier Messiaen, 72085 Le Mans Cedex 9, France.
Describing the crystal structure of disordered materials with mixed-occupancy crystallographic sites is essential for understanding their physicochemical properties and designing new materials tuned to their targeted functionalities. Here, we investigate the structure of RbMOF (M = Nb, Ta) pyrochlore-type oxyfluorides using a multimodal approach that combines experimental and computational techniques. Rietveld structural refinement of powder X-ray powder diffraction (PXRD) data confirmed that these oxyfluorides are isostructural, and their average crystal structure is disordered.
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