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BMJ Case Rep
January 2025
Department of Internal Medicine, Dermatology Unit, Mbeya Zonal Referral Hospital, Mbeya, United Republic of Tanzania.
A man in his early 50s from Tanzania presented with chronic nodular skin lesions and joint pain, likely due to gout complicated by obesity, after over 15 years of misdiagnosis and ineffective treatment. Despite various therapies for leprosy, tuberculosis and steroid use, his condition worsened, leading to hyperglycaemia and significant financial strain. Missed opportunities to use simple, low-cost diagnostic tests such as ultrasound and examining nodule fluid for urate crystals led to delays in diagnosis.
View Article and Find Full Text PDFTher Umsch
September 2024
Rheuma- und Osteoporose-Zentrum Kloten Kalchengasse 7 8302 Kloten.
Gout is a common form of inflammation, characterized by sudden, severe attacks of pain, swelling, redness and tenderness. The diagnosis is based on the typical clinical pattern, but the definitive diagnosis requires the identification of urat crystals in the joint fluid or in ultrasound or DECT. The differential diagnosis includes always infection or other crystal arthropathies, in atypical presentation also other forms of arthritis, e.
View Article and Find Full Text PDFFront Immunol
March 2024
Department of Dermatology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China.
Multicentric reticulohistiocytosis (MRH) is a rare systemic disorder characterized by histiocytic hyperplasia that mainly involves the skin, mucous membranes, and joints. The typical clinical features include papules, nodules, and arthritis. MRH lesions are relatively extensive but small and scattered.
View Article and Find Full Text PDFWorld Neurosurg
February 2024
Department of Neurosurgery, Center for Neurosciences and Spine, Virginia Mason Franciscan Health, Seattle, Washington, USA.
Background: This study describes a rare case where gout, a condition primarily associated with joint inflammation, initially manifested as a progressive cervical kyphotic deformity, mimicking infection and causing myelopathy. The patient, a previously healthy 56-year-old woman, presented with severe jaw pain and a temporomandibular joint abscess, alongside 2 months of worsening balance and arm/hand tingling. Extensive clinical and radiographic assessments revealed a severe cervical kyphotic deformity with bony erosion at multiple vertebral levels, raising suspicion of an infectious cause of compressive myelopathy.
View Article and Find Full Text PDFWorld J Clin Cases
October 2023
Department of Plastic and Reconstructive Surgery, DongGuk University Medical Center, GoYang 10326, South Korea.
Background: Gout is a common type of inflammatory arthritis caused by the deposition of monosodium urate crystals in the joints and surrounding tissues. It typically appears with abrupt and intense pain, redness, and swelling in the affected joint. It frequently targets the lower extremities, such as the big toe.
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