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AP2A1 modulates cell states between senescence and rejuvenation.
Cell Signal
January 2025
Division of Bioengineering, Graduate School of Engineering Science, University of Osaka, Japan; R(3) Institute for Newly-Emerging Science Design, University of Osaka, Japan; Global Center for Medical Engineering and Informatics, University of Osaka, Japan. Electronic address:
Aging proceeds with the accumulation of senescent cells in multiple organs. These cells exhibit increased size compared to young cells, which promotes further senescence and age-related diseases. Currently, the molecular mechanism behind the maintenance of such huge cell architecture undergoing senescence remains poorly understood.
View Article and Find Full Text PDFWernicke encephalopathy in a patient with drug-induced liver failure: a case report.
Front Nutr
January 2025
Department of Infectious Diseases, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
Introduction: Wernicke encephalopathy is a metabolic disease mainly associated with vitamin B1 deficiency, which is common in chronic alcoholism. Non-alcoholic Wernicke encephalopathy is difficult for early diagnosis.
Case Presentation: One case involved a 62-year-old man who was admitted to hospital with drug-induced liver failure.
Acquired Dyschromatopsia and Its Link to Drug Toxicity.
Cureus
December 2024
Optometric - Glaucoma, Leicester Royal Infirmary, Leicester, GBR.
Colour vision defects (CVDs) can be both congenital and acquired, with acquired dyschromatopsia often associated with medication toxicity. This review explores various standardised colour vision tests used to detect these defects, including the Ishihara plate test, Farnsworth-Munsell 100 hue test, and anomaloscopes. These methods are evaluated for their effectiveness in diagnosing CVDs, particularly in acquired conditions.
View Article and Find Full Text PDFGenetic analyses identify brain functional networks associated with the risk of Parkinson's disease and drug-induced parkinsonism.
Cereb Cortex
January 2025
Institute of Neurology, Anhui University of Chinese Medicine, No. 357 Changjiang Middle Road, Luyang District, Hefei 230061, China.
Brain functional networks are associated with parkinsonism in observational studies. However, the causal effects between brain functional networks and parkinsonism remain unclear. We aimed to assess the potential bidirectional causal associations between 191 brain resting-state functional magnetic resonance imaging (rsfMRI) phenotypes and parkinsonism including Parkinson's disease (PD) and drug-induced parkinsonism (DIP).
View Article and Find Full Text PDFA reply, drug-induced reversible cerebral vasoconstriction syndrome: Lessons from the real world.
Cephalalgia
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Service de Pharmacologie Clinique, Centre Régional de Pharmacovigilance, CHU Poitiers, Poitiers, France.
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