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A Post-Mortem Molecular Damage Profile in the Ancient Human Mitochondrial DNA.
Mol Ecol Resour
January 2025
Research Group in Biological Anthropology, Biological Anthropology Unit, Department of Animal Biology, Vegetal Biology and Ecology, Universitat Autònoma de Barcelona, Barcelona, Spain.
Mitochondrial DNA (mtDNA) analysis is crucial for understanding human population structure and genetic diversity. However, post-mortem DNA damage poses challenges, that make analysis difficult. DNA preservation is affected by environmental conditions which, among other factors, complicates the differentiation of endogenous variants from artefacts in ancient mtDNA mix profiles.
View Article and Find Full Text PDFVavro Šrobár: Slovak politician and publicist as a medical doctor involved (also) in the history of medicine.
J Med Biogr
December 2024
Institute of Social Medicine and Medical Ethics, Faculty of Medicine, Comenius University in Bratislava, Bratislava, Slovakia.
Vavro Šrobár was a prominent political figure in East-Central Europe. He played a pivotal role in the establishment and development of the First Czechoslovak Republic, which emerged following the dissolution of the Austro-Hungarian Empire. He was the first Minister to exercise full administrative authority in overseeing the Provisional Government of Slovakia, and throughout his career, including until the end of his life, he held several significant political positions, such as Minister of Public Health and Physical Education, Minister of Unification, Minister of Education and National Enlightenment, and Minister of Finance.
View Article and Find Full Text PDFPermafrost thaw subsidence, sea-level rise, and erosion are transforming Alaska's Arctic coastal zone.
Proc Natl Acad Sci U S A
December 2024
Alfred Wegener Institute Helmholtz-Centre for Polar and Marine Research, Permafrost Section, Potsdam 14401, Germany.
Article Synopsis
- Arctic shorelines are increasingly vulnerable to climate change due to rising sea levels, thawing permafrost, and worsening storms, leading to significant coastal erosion.
- Past observations have primarily focused on erosion, neglecting the combined effects of sea-level rise and permafrost thaw subsidence, particularly in areas like Alaska's Arctic Coastal Plain, which is essential for Indigenous communities and oil infrastructure.
- Projections indicate that by 2100, combined erosion and inundation could result in 6-8 times more land loss than erosion alone, potentially damaging 40-65% of infrastructure in coastal villages and emphasizing the urgent need for adaptive planning to address these climate hazards.
Scalable, data-assimilated models predict large-scale shoreline response to waves and sea-level rise.
Sci Rep
November 2024
U.S. Geological Survey, Santa Cruz, USA.
Coastal change is a complex combination of multi-scale processes (e.g., wave-driven cross-shore and longshore transport; dune, bluff, and cliff erosion; overwash; fluvial and inlet sediment supply; and sea-level-driven recession).
View Article and Find Full Text PDFLong-term coastal dynamics: The evolution of a mixed sediment mega-nourishment consisting of colliery spoil.
J Environ Manage
December 2024
School of Engineering, Newcastle University, Newcastle Upon Tyne, UK.
Mega-nourishments, where large volumes of sediment are deposited on coastlines, are increasingly employed to manage shoreline erosion, yet our understanding of their long-term behaviour is limited by the fact that most current schemes are less than 15 years old. However, on the County Durham coast, 39 million m of coal spoil was tipped onto beaches between the late 1800s and 1993, acting as a de facto mixed sediment mega-nourishment. Our findings reveal key insights into the long-term dynamics of mega-nourishment schemes, including evidence of effective sediment dispersal around headlands into normally disconnected units of coast.
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