On the basis of the literature a postulate is proposed that the immune system contributes to regulating the intensity and direction of endocrine and nervous system functions in normal conditions and after the effect of ionizing radiation. The role of neuroimmunoendocrine interactions and their impairment in the realization of stochastic and nonstochastic sequelae of irradiation at various levels of radiation affecting the organism under normal conditions and in a combination with other unfavourable factors.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Photo-neuro-immuno-endocrinology: How the ultraviolet radiation regulates the body, brain, and immune system.
Proc Natl Acad Sci U S A
April 2024
Comprehensive Cancer Center, Cancer Chemoprevention Program, University of Alabama at Birmingham, Birmingham, AL 35294.
Ultraviolet radiation (UVR) is primarily recognized for its detrimental effects such as cancerogenesis, skin aging, eye damage, and autoimmune disorders. With exception of ultraviolet B (UVB) requirement in the production of vitamin D3, the positive role of UVR in modulation of homeostasis is underappreciated. Skin exposure to UVR triggers local responses secondary to the induction of chemical, hormonal, immune, and neural signals that are defined by the chromophores and extent of UVR penetration into skin compartments.
View Article and Find Full Text PDFCutaneous-immuno-neuro-endocrine (CINE) system: A complex enterprise transforming skin into a super organ.
Exp Dermatol
March 2024
Department of Immunopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Skin is now emerging as a complex realm of three chief systems viz. immune system, nervous system, and endocrine system. The cells involved in their intricate crosstalk, namely native skin cells, intra-cutaneous immune cells and cutaneous sensory neurons have diverse origin and distinct functions.
View Article and Find Full Text PDFThe Impact of Lifestyle on the Immune System: Focus on Islamic Lifestyle: A Narrative Review.
Int J Prev Med
August 2023
Department of Cell and Molecular Biology and Microbiology, Faculty of Biological Sciences and Technology, University of Isfahan, Isfahan, Iran.
"Lifestyle" is the way or style of people living in a special time and place and includes behaviors and functions of individuals which are formed in a specific geographical, economic, political, cultural, and religious context and influenced by them. Lifestyle as an essential and efficient agent, impacts different aspects of human health, including immune functions. In the Islamic lifestyle, many recommendations have beneficial effects on human health.
View Article and Find Full Text PDFHepatic Oxi-Inflammation and Neophobia as Potential Liver-Brain Axis Targets for Alzheimer's Disease and Aging, with Strong Sensitivity to Sex, Isolation, and Obesity.
Cells
May 2023
Institut de Neurociències, Universitat Autònoma de Barcelona, 08193 Barcelona, Spain.
Research on Alzheimer's disease (AD) has classically focused on alterations that occur in the brain and their intra- and extracellular neuropathological hallmarks. However, the oxi-inflammation hypothesis of aging may also play a role in neuroimmunoendocrine dysregulation and the disease's pathophysiology, where the liver emerges as a target organ due to its implication in regulating metabolism and supporting the immune system. In the present work, we demonstrate organ (hepatomegaly), tissue (histopathological amyloidosis), and cellular oxidative stress (decreased glutathione peroxidase and increased glutathione reductase enzymatic activities) and inflammation (increased IL-6 and TNF𝛼) as hallmarks of hepatic dysfunction in 16-month-old male and female 3xTg-AD mice at advanced stages of the disease, and as compared to age- and sex-matched non-transgenic (NTg) counterparts.
View Article and Find Full Text PDFProgress on traditional Chinese medicine in treatment of ischemic stroke via the gut-brain axis.
Biomed Pharmacother
January 2023
College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China; Shandong Co-innovation Center of Classic Traditional Chinese Medicine Formula, Shandong University of Traditional Chinese Medicine, Jinan, China. Electronic address:
Ischemic stroke is a common issue that severely affects the human health. Between the central nervous system and the enteric system, the " Gut-Brain " axis, the bidirectional connection involved in the neuro-immuno-endocrine network, is crucial for the occurrence and development of ischemic stroke. Ischemic stroke can lead to change in the gut microbiota and gastrointestinal hormones, which will then reversely affect the disease development.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!