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Famished for Freedom: Pellagra and Medical Clemency at the Mississippi State Penitentiary.
J Hist Med Allied Sci
January 2025
University of Wisconsin-Madison, Wisconsin, USA.
This paper provides a case study of one medical experiment conducted in 1915 by the United States Public Health Service in collaboration with the Mississippi State Penitentiary. The experiment was non-therapeutic and its objective was to induce pellagra (a vitamin deficiency disease) in twelve healthy White male prisoners to confirm its etiology. Extant archival records produced by the convict participants, state politicians, and health researchers underscore that the men selected for the pellagra experiment were unique among incarcerated people in Mississippi at the time: they were White, wealthy, and politically well-connected.
View Article and Find Full Text PDFAtypical presentation of pellagra with black urine: A clinical conundrum.
SAGE Open Med Case Rep
July 2024
University Medical Unit, Colombo South Teaching Hospital, Kalubowila, Sri Lanka.
Article Synopsis
- - Niacin (Vitamin B3) is vital for energy production, metabolism, and DNA repair, with severe deficiency leading to a condition called pellagra, which can cause dermatitis, dementia, diarrhea, and death if untreated.
- - A case involved a 68-year-old woman with symptoms like photosensitive dermatitis and abdominal pain, prompting diagnostic tests that ruled out porphyria cutanea tarda.
- - Ultimately, she was diagnosed with pellagra, and prompt treatment resulted in a complete recovery, highlighting the importance of timely diagnosis and management of this potentially fatal condition.
Roux-en-Y Gastric Bypass and the Clinical Manifestations of Vitamin Deficiencies: Case Report and Literature Review.
Cureus
March 2024
Infectious Diseases, Quillen College of Medicine at East Tennessee State University, Johnson City, USA.
Article Synopsis
- A 45-year-old female patient experienced serious complications after Roux-en-Y gastric bypass surgery (RYGBS), including weakness, hypotension, and inability to eat, leading to significant weight loss and bedridden status.
- She presented to the hospital with signs of dehydration and vitamin deficiencies, such as Pellagra and Bitot spots, as well as low protein and electrolyte imbalances.
- After being treated in the ICU and undergoing an endoscopy that revealed an anastomotic stricture, she was placed on Total Parenteral Nutrition (TPN) and discharged with education on vitamin supplementation and the importance of regular follow-up care.
The Pellagra Portraits.
JAMA
February 2024
Department of Medical History and Bioethics, School of Medicine and Public Health, University of Wisconsin, Madison.
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