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An Integrating Model for Rapid Reduction of Maternal Mortality Due to Primary Postpartum Haemorrhage - Novel Use of the Catalyst Approach to Public Health.
Afr J Reprod Health
June 2019
Director General of Reproductive Health, Ministry of Health, Niamey, Niger.
On average 16%-53% of maternal deaths are from postpartum haemorrhage (PPH), with confidence intervals for Eastern Asia reaching beyond 60%. Success in preventing PPH mortality across many large low-resource populations has been fairly limited. Niger's government and an international non-governmental organization (NGO) have developed a model aiming to rapidly reduce primary postpartum haemorrhage mortality, combining relatively new technologies, misoprostol, condom tamponade, and non- inflatable anti-shock garment, with systematic measurement of blood loss and a set of traditional public health tools that constitute the Catalyst Approach to Public Health, with action steps for each phase if haemorrhage occurs.
View Article and Find Full Text PDFMisoprostol, Magnesium Sulphate and Anti-shock garment: A knowledge, availability and utilization study at the Primary Health Care Level in Western Nigeria.
PLoS One
December 2019
Department of Community Health and Primary Care, College of Medicine, University of Lagos, Lagos, Nigeria.
Introduction: Nigeria has one of the highest maternal mortality ratios in the world. The nurses and midwives being the first point of contact play a central role in addressing these problems. This study was conducted to assess the knowledge and utilization of the technologies (misoprostol, anti-shock garment and magnesium sulphate) in the reduction of maternal mortality amongst the Primary Health Care (PHC) nurses and midwives in Lagos State, Nigeria.
View Article and Find Full Text PDFThe novel strategy of glucocorticoid drug development via targeting nongenomic mechanisms.
Steroids
October 2015
Department of Rheumatology and Clinical Immunology, Charité University Hospital, 10117 Berlin, Germany. Electronic address:
Glucocorticoids (GCs) are widely used in clinical practice as potent anti-inflammatory and immunosuppressive agents. Unfortunately, they can also produce numerous and potentially serious side effects that limit their usage. This problem represents the driving force for the intensive search for novel GCs with a better benefit-risk ratio compared to conventional GCs.
View Article and Find Full Text PDF[On the key point in improving the level of burn treatment from the five aspects of PRIDE].
Zhonghua Shao Shang Za Zhi
June 2013
Institute of Burn Research, Southwest Hospital, State Key Laboratory of Trauma, Burns and Combined Injury, the Third Military Medical University, Chongqing 400038, China.
The "PRIDE"-five combined measures, including "protection of cell function and anti-shock treatment to reduce ischemic-hypoxic injury", "rehabilitation from early postburn stage", "inhalation injury treatment", "deep burn wound repair", and "enterogenous infection control", are key measures to improve the levels of burn treatment. The progressive advances in combined measures denoted as "PRIDE" have raised the burn treatment to a higher level and greatly elevated the survival rate. The degree of attention has also been raised from improvement in survival rate only to higher survival rate and better life quality with improvement in rehabilitation.
View Article and Find Full Text PDFCardiac variation of inferior vena cava: new concept in the evaluation of intravascular blood volume.
J Med Ultrason (2001)
July 2013
Department of Emergency and Critical Care Medicine, The University of Tokyo Hospital, 7-3-1 Hongo Bunkyo, Tokyo, 113-8655, Japan.
Evaluation of the intravascular blood volume is an important assessment in emergency and critical care medicine. Measurement of the inferior vena cava (IVC) respiratory variation by ultrasound echography is useful, but it entails subjective problems. We have hypothesized that IVC cardiac variation is also correlated with intravascular blood volume and analyzed it automatically using computer software of two kinds, later comparing the results.
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