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Case Report: Baricitinib improved alopecia areata in a pediatric patient with atopic dermatitis.
Front Pediatr
January 2025
Department of Dermatology, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang Province, China.
Article Synopsis
- Alopecia areata (AA) is a non-scarring hair loss condition, often seen in children with atopic dermatitis (AD), and its exact cause remains unclear.
- A case study of a child with myasthenia gravis showed severe AA and moderate AD, which improved significantly after a year of treatment with baricitinib and corticosteroid ointment, with a notable drop in severity scores and visible hair regrowth.
- The study highlights the potential of Janus kinase inhibitors in treating pediatric AA and AD, emphasizing the safety and lack of significant adverse effects during the treatment, except for mild folliculitis.
Phytochemical investigation, role in wound healing process and cytotoxicity of Sphagneticola trilobata: In vitro, in vivo and in silico approach.
J Ethnopharmacol
January 2025
Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Kasr-El-Ainy, Cairo 11562, Egypt. Electronic address:
Ethnopharmacological Relevance: Sphagneticola trilobata was traditionally used to alleviate wounds using topical plant preparations. The precise mechanism of the plant responsible for its wound healing effect are still unclear. Although the plant was reported to be cytotoxic, there is a lack of reported data regarding its cytotoxic impact on skin cancer.
View Article and Find Full Text PDFEffects of topical neutral protamine Hagedorn insulin on corneal wound healing: an experimental study in rabbits.
Biotech Histochem
January 2025
Faculty of Veterinary Medicine, Department of Pathology, Siirt University, Siirt, Turkiye.
Corneal injuries are common in human and veterinary ophthalmology. There are many studies which have investigated the treatment of corneal epithelial defects. This study aimed to investigate the effects of Neutral Protamine Hagedorn (NPH) insulin as an ointment for wound healing in experimental corneal defects.
View Article and Find Full Text PDFPatients presenting with severe acute cardiogenic pulmonary edema with hypoxia commonly require intubation until heart failure treatments take effect. A new term describing similar condition is called sympathetic crashing acute pulmonary edema (SCAPE). It is also called Flash pulmonary edema.
View Article and Find Full Text PDF[Research progress in acupoint administration of new dosage forms of traditional Chinese medicine preparations for rheumatoid arthritis].
Zhongguo Zhong Yao Za Zhi
December 2024
College of Pharmaceutical Sciences, Guizhou University of Traditional Chinese Medicine Guiyang 550025, China National Engineering Technology Research Center for Miao Medicine Guiyang 550025, China Guizhou Engineering Technology Research Center for Processing and Preparation of Traditional Chinese Medicine and Ethnic Medicine Guiyang 550025, China.
The conventional acupoint therapy for rheumatoid arthritis often uses traditional Chinese medicine preparations in the dosage forms of powder, ointment, and paste. However, these dosage forms have obvious drawbacks, such as low transdermal absorption, strong skin irritation, and easy detachment. Creating a traditional Chinese medicine acupoint therapy characterized by high penetration, low toxicity, low irritation, and convenient administration is of great significance.
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