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Exploring the impact of exercise-induced BDNF on neuroplasticity in neurodegenerative and neuropsychiatric conditions.
Mol Biol Rep
January 2025
Department of Nursing Science, Faculty of Basic Medical Sciences, Adeleke University, Ede, Osun State, Nigeria.
This review investigates the intricate relationship between exercise, brain-derived neurotrophic factor (BDNF), neuroplasticity, and cognitive function, with a focus on implications for neuropsychiatric and neurodegenerative disorders. A systematic review was conducted by searching various databases for relevant studies that explored the connections between exercise, BDNF, neuroplasticity, and cognitive health. The analysis of eligible studies revealed that exercise increases BDNF levels in the brain, promoting neuroplasticity and enhancing cognitive functions.
View Article and Find Full Text PDFCovert consciousness in critical care.
Intensive Care Med
January 2025
Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Prospective Harmonization, Common Data Elements, and Sharing Strategies for Multicenter Pre-Clinical Traumatic Brain Injury Research in the Translational Outcomes Project in Neurotrauma Consortium.
J Neurotrauma
January 2025
Division of Neuroscience, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH), Bethesda, Maryland, USA.
Effective team science requires procedural harmonization for rigor and reproducibility. Multicenter studies across experimental modalities (domains) can help accelerate translation. The Translational Outcomes Project in NeuroTrauma (TOP-NT) is a pre-clinical traumatic brain injury (TBI) consortium charged with establishing and validating noninvasive TBI assessment tools through team science.
View Article and Find Full Text PDFModified 'Xingnao Kaiqiao' acupuncture technique shortens the recovery time of comatose patients.
Ann Med
December 2025
Department of TCM, The First People's Hospital of Zunyi (The Third Affiliated Hospital of Zunyi Medical University), Zunyi City, Guizhou Province, China.
Background: This study was conducted to analyse the therapeutic effect of the modified 'Xingnao Kaiqiao' acupuncture technique in the recovery of comatose patients, as well as the clinical factors that may influence recovery from coma.
Methods: Diagnostic and therapeutic data from 166 patients in a coma due to neurological diseases were retrospectively collected. Eighty-seven comatose patients received conventional treatment, and 79 patients received conventional treatment + the modified 'Xingnao Kaiqiao' acupuncture technique.
[Connectome in stroke patients].
Zh Nevrol Psikhiatr Im S S Korsakova
January 2025
Pirogov Russian National Research Medical University (Pirogov University), Moscow, Russia.
Stroke is the main cause of disability among neurological diseases. There are questions of the accuracy of topical diagnosis and rehabilitation prognosis in clinical practice. Answers to these questions may be given by an approach to the study of the nervous system as a dynamic network consisting of a set of brain regions with anatomical and functional connections between them.
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