Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Urothelial carcinoma in situ with "early papillary formation" vs "lateral spread/shoulder lesion" of prior high-grade noninvasive papillary urothelial carcinoma: A survey of pathologist and urologist interpretations.
Am J Clin Pathol
December 2024
Department of Pathology and Laboratory Medicine, Cleveland Clinic Foundation, Cleveland, OH, United States.
Objectives: Urothelial carcinoma in situ (CIS) with early papillary formation is terminology sometimes used to suggest incipient high-grade papillary urothelial carcinoma (PUC) but may lead to confusion between true CIS and lateral flat spread of PUC.
Methods: It remains unclear how pathologists and urologists interpret this scenario, so a survey was circulated to 68 pathologists (group 1 = 28 academic genitourinary pathologists; group 2 = 17 pathologists with a self-reported genitourinary focus; group 3 = 23 pathologists self-reported as not genitourinary specialists) and 32 urologists.
Results: Regarding atypical urothelial lesions that appear mainly flat but contain possible papillae, group 3 was more likely to label this as CIS compared with groups 1 and 2 (35% for group 3 vs 13% for groups 1 and 2), while groups 1 and 2 more often adopted another descriptive diagnosis, such as "CIS with early papillary features" (38% for groups 1 and 2 vs 13% for group 3).
'Eczematous' dermatitis of the nipple: clinical and histopathological differential diagnosis of Paget disease.
Pathology
April 2024
University of Rochester Medical Center, Department of Pathology and Laboratory Medicine, Rochester, NY, USA; University of Rochester Medical Center, Department of Dermatology, Rochester, NY, USA.
The nipple can be affected by many malignant and benign entities. A wide variety of diseases including Paget disease, atopic dermatitis and nipple candidiasis can cause eczema-like changes in the nipple. In cases of diagnostic uncertainty, tissue sampling may be indicated.
View Article and Find Full Text PDFClinical and histopathological features of lentigo maligna and lentigo maligna melanoma: a retrospective analysis in Korea.
Front Med (Lausanne)
January 2024
Seoul National University College of Medicine, Seoul, Republic of Korea.
Article Synopsis
- The study focused on lentigo maligna (LM) and lentigo maligna melanoma (LMM), which are rare skin conditions in Asian countries, and aimed to identify histopathological features to differentiate them from benign lentigo.
- Researchers analyzed 21 patients diagnosed with LM/LMM from 2011-2022 to assess their histopathologic characteristics based on 16 criteria, comparing them with benign cases.
- Significant differences were found between LM/LMM and benign lentigo in several features, such as asymmetry, cytologic atypia, and invasion patterns, highlighting diagnostic challenges in histopathological assessments.
Constant small-cell changes and variable LEF1 expression in DUSP22-rearranged primary cutaneous anaplastic large-cell lymphoma: Analysis of the repeated biopsies of three patients.
Pathol Int
September 2023
Department of Diagnostic Pathology, Kyoto University Hospital, Kyoto, Japan.
DUSP22-rearranged primary cutaneous anaplastic large-cell lymphoma (pcALCL) has a biphasic histological pattern defined by large dermal atypical lymphocytes and epidermotropic small lymphocytes resembling pagetoid reticulosis, but the positivity rate of the biphasic pattern in DUSP22-rearranged pcALCL is unknown. Immunohistochemically, LEF1 expression in >75% of tumor cells is associated with DUSP22-rearrangement (DUSP22-R) in systemic ALCL. However, whether this association applies to pcALCL remains unclear.
View Article and Find Full Text PDFPagetoid Squamous Cell Carcinoma In-Situ of Esophagus.
Kathmandu Univ Med J (KUMJ)
August 2024
Samyak Pathology Lab, New Baneshwor, Kathmandu, Nepal.
Squamous cell carcinoma (SCC) is the most common malignant tumor of the esophagus, however, pagetoid SCCIS is an extremely rare condition in esophagus.1 Pagetoid Squamous Cell Carcinoma In-Situ (SCCIS) has been described in skin and external genitalia frequently.2 Herein we report a case of pagetoid squamous cell carcinoma in-situ in a 50-year-old male with clinical information, histopathological and immunohistochemical findings.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!