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Biometric Technology at the Borders of Citizenship: Identifying Technical Standards for Introducer-Based Remote Onboarding in Global Contexts of Statelessness, Nomadism, Displacement, and Refuge.
Int J Digit Law Gov
October 2024
Trustworthy Digital Infrastructure for Identity Systems, The Alan Turing Institute, London, UK.
All throughout the so-called "Global South", hundreds of millions of individuals from entire communities in the rural, poorer, or most peripheral areas are not officially recorded by the States they are citizens of or they habitually reside in. This is why several of such States are resorting to extensive and purportedly "universal" digital remote onboarding programs, pioneered by India's Aadhaar, whereby individuals are centrally recorded onto a public database with their identity (and possibly citizenship) confirmed. Whenever paper documents are obsolete, inaccurate, deteriorated, or inexistent, individuals may have their identity confirmed through an "introducer", who mediates between marginalised communities and central authorities and is entrusted by both with this delicate task.
View Article and Find Full Text PDFAccrual Suspensions in Seamless Phase II/III Trials: A Review of NRG Oncology Trials.
JCO Oncol Adv
December 2024
Biometric Research Program, National Cancer Institute, Bethesda, MD.
Purpose: A phase II/III trial is a type of phase III trial that has embedded in it an intermediate phase II go/no-go decision as to whether to continue the accrual to the phase III sample size. We examine the design characteristics and experience of a well-defined set of National Cancer Institute phase II/III trials, with special emphasis on designed accrual suspensions while awaiting the data to become mature enough for the phase II analysis. This experience is used to highlight the potential of using a calendar backstop to avoid an inordinately long accrual suspension.
View Article and Find Full Text PDFDifferences between Current Clinical Practice and Evidence-Based Guideline Recommendations Regarding Tocolysis - an Austria-wide Survey.
Geburtshilfe Frauenheilkd
January 2025
Department of Gynecology, Obstetrics, and Gynecological Endocrinology, Kepler University Hospital, Johannes Kepler University Linz, Linz, Austria.
Introduction: To evaluate the adherence of Austrian obstetricians to national guideline recommendations by investigating data on the current practice of tocolysis regarding indications, timing and monitoring of tocolysis, choice of tocolytics and serious side effects, maintenance tocolysis, support of decision-making and recommendations at patient's discharge from the hospital.
Materials And Methods: 78 obstetric departments in Austria were invited to participate in a nationwide survey between June 5 and August 31 2023 by answering a web-based questionnaire about clinical standards. The survey was conducted approximately one year after implementation of the AWMF Guideline "Prevention and Therapy of Preterm Birth" 015‑025.
3D Finite Element Modeling of Femtosecond Laser Trabeculotomy.
Lasers Surg Med
January 2025
ViaLase Inc., Aliso Viejo, California, USA.
Objectives: Femtosecond laser image guided high precision trabeculotomy (FLigHT) is a novel open-angle glaucoma treatment. The procedure non-invasively creates aqueous humor (AH) drainage channel from the anterior chamber (AC) to Schlemm's canal (SC) through the trabecular meshwork (TM) to decrease intraocular pressure (IOP). The purpose of this study was to develop a 3D finite element model (FEM) of the FLigHT procedure and to simulate clinical results for different drainage channel cross-sectional areas.
View Article and Find Full Text PDFEffect of intramuscular treatment with different iron dextran dosages and non-inferiority study to gleptoferron.
Acta Vet Scand
January 2025
Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Grønnegårdsvej 2, 1870, Frederiksberg C, Denmark.
Background: Prevention of iron deficiency in suckling piglets by intramuscular injection of a standardized amount of iron dextran or gleptoferron in the first days of life can lead to over- or underdosage with respective health risks. Currently, combined iron products containing an active substance against coccidia are also used on farms. When using a combination product targeting two diseases, an adjustment of the necessary amount of iron to prevent anaemia in the frame of a farm-specific treatment protocol is not possible.
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