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Turbinate loss from non-inflammatory sinonasal surgery does not correlate with poor sinonasal function.
Am J Otolaryngol
April 2020
Rhinology and Skull Base Research Group, Applied Medical Research Centre, University of New South Wales, Sydney, Australia; Department of Otolaryngology, Concord Repatriation General Hospital, University of Sydney, Sydney, Australia; Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.
Objective: The impact of turbinate resection on nasal function remains a controversial topic. In surgery for inflammatory sinonasal disease, turbinate resection is often avoided. In contrast, turbinate tissue is routinely sacrificed in endoscopic tumor and skull base surgery to achieve negative margins or gain adequate exposure.
View Article and Find Full Text PDFEsophageal A-ring is associated with the severity of gastroesophageal reflux.
Laryngoscope
April 2020
Department of Otolaryngology-Head and Neck Surgery, University of California Davis, Sacramento, California, U.S.A.
Background: The esophageal A-ring (EAR) is an anatomic finding appreciated on videofluoroscopic esophagram (VFE) at the junction of the tubular esophagus and esophageal vestibule. EARs are appreciated on a small subset (5%) of VFEs. We hypothesize that EARs represent a compensatory mechanism to protect against gastroesophageal reflux (GER).
View Article and Find Full Text PDFDownbeat nystagmus due to ranitidine in a pediatric patient.
Eur J Paediatr Neurol
July 2017
Department of Pediatrics, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Background: Ranitidine has not been considered as a potential cause of ocular movement conditions. However, it is known that the vestibular nucleus complex, that has a key role in gaze control and vestibule-ocular reflexes, receives hypothalamic histaminergic innervations. Some studies reported the effect of ranitidine blocking the excitatory responses of vestibular nuclei neurons to histamine.
View Article and Find Full Text PDFNatural capsaicinoids improve swallow response in older patients with oropharyngeal dysphagia.
Gut
September 2013
Centro de Investigación Biomedica en Red de enfermedades hepáticas y digestivas (CIBERehd), Instituto de Salud Carlos III, Barcelona, Spain.
Objective: There is no pharmacological treatment for oropharyngeal dysphagia (OD). The aim of this study was to compare the therapeutic effect of stimulation of oropharyngeal transient receptor potential vanilloid type 1 (TRPV1) with that of thickeners in older patients with OD.
Design: A clinical videofluoroscopic non-randomised study was performed to assess the signs of safety and efficacy of swallow and the swallow response in (1) 33 patients with OD (75.
Effects of simulated reflux laryngitis on laryngeal chemoreflexes in newborn lambs.
J Appl Physiol (1985)
August 2011
Department of Pediatrics, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
It has been suggested that reflux laryngitis (RL) is involved in apneas-bradycardias of the newborn. The aim of the present study was to develop a unique RL model in newborn lambs to test the hypothesis that RL enhances the cardiorespiratory components of the laryngeal chemoreflexes (LCR) in the neonatal period. Gastric juice surrogate (2 ml of normal saline solution with HCl pH 2 + pepsin 300 U/ml) (RL group, n = 6) or normal saline (control group, n = 6) was repeatedly injected onto the posterior aspect of the larynx, 3 times a day for 6 consecutive days, via a retrograde catheter introduced into the cervical esophagus.
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