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Reply to 'Aetiology and clinical manifestations of patients with non-dilated left ventricular cardiomyopathy. Some comments'.
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Inherited and Rare Cardiovascular Diseases, Department of Translational Medical Sciences, University of Campania 'Luigi Vanvitelli', Monaldi Hospital, Naples, Italy.
Inherited genome instability.
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Spanish National Cancer Research Center (CNIO), Madrid, Spain.
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View Article and Find Full Text PDFAnalysis of contemporary value and influence of intangible cultural heritage based on online review mining.
PLoS One
December 2024
College of Economics and Management, Zhejiang Normal University, Jinhua, Zhejiang Province, China.
Purpose: The development of new media has enabled intangible cultural heritage to be disseminated through online platforms and attracted the attention of many contemporary young people. Classification and discussion on the value of intangible cultural heritage is an important way to help the inheritance and dissemination.
Design/methodology/approach: Real online reviews were collected based on the Bilibili website as the research data source.
Evolutionary analysis of CBFs/DREB1s in temperate and tropical woody bamboos and functional study of PeDREB1A3 under cold and drought stress.
Plant Physiol Biochem
December 2024
State Key Laboratory of Subtropical Silviculture, Zhejiang A&F University, Hangzhou, 310000, China; Bamboo Industry Institute, Zhejiang A&F University, Hangzhou, 310000, China. Electronic address:
Bamboo forests are vulnerable to extreme cold, as well as drought caused by declining rainfall or persistent hot, under global climate change. The C-repeat binding factors/dehydration-responsive element binding protein 1s (CBFs/DREB1s) are vital to acquiring tolerance to deal with the changing climate in plants. Herein, we investigated the evolution of CBFs/DREB1s in four temperate or tropical woody bamboos.
View Article and Find Full Text PDFPredictive Power of Polygenic Risk Scores for Intraocular Pressure or Vertical Cup-Disc Ratio.
JAMA Ophthalmol
January 2025
Queensland Institute of Medical Research Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Importance: Early detection of glaucoma is essential to timely monitoring and treatment, and primary open-angle glaucoma risk can be assessed by measuring intraocular pressure (IOP) or optic nerve head vertical cup-disc ratio (VCDR). Polygenic risk scores (PRSs) could provide a link between genetic effects estimated from genome-wide association studies (GWASs) and clinical applications to provide estimates of an individual's genetic risk by combining many identified variants into a score.
Objective: To construct IOP and VCDR PRSs with clinically relevant predictive power.
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