Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/0002-9394(58)90649-4 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The involvement of YAP-TGFβ-SMAD-mediated fibrosis in primary inferior oblique overaction.
Biochim Biophys Acta Mol Basis Dis
December 2024
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou 510060, China. Electronic address:
This study investigates the involvement of fibrosis in primary inferior oblique overaction (PIOOA), a strabismus characterized by excessive upward eye rotation. First, we identified extensive fibrotic changes in inferior oblique (IO) muscles in PIOOA patients compared to normal controls. A strong positive correlation was clinically established between the severity of PIOOA and the expression of collagen type I alpha 1 chain (COL1A1).
View Article and Find Full Text PDFZNF197-AS1/miR-425/GABARAPL1 axis: a novel regulatory mechanism in uveal melanoma.
Am J Physiol Cell Physiol
December 2024
Department of Orbital Disease and Ocular Plastic Surgery, The Second Hospital of Jilin University, Changchun, People's Republic of China.
This study investigates the role of the long noncoding RNA (lncRNA) in uveal melanoma (UM), focusing on its function within a competing endogenous RNA (ceRNA) network. Using the UM-related TCGA (The Cancer Genome Atlas) dataset, we analyzed the expression levels of and its correlation with and , an essential autophagy-related gene. Our analysis revealed that acts as a ceRNA by competitively binding to , resulting in the upregulation of .
View Article and Find Full Text PDFPurpose: To investigate the inhibition of myopia progression and axial elongation in children wearing orthokeratology (OK) lenses, as well as to evaluate the status of corneal reshaping, this study explores the relationship between changes in central corneal curvature (K-value) and e-value induced by OK lenses and axial elongation.
Methods: In this study, it is planned to select children aged 8-15 who wear orthokeratology lenses at the Pediatric Ophthalmology and Strabismus Clinic of the Second Affiliated Hospital of Dalian Medical University. All children will undergo slit lamp examination, visual acuity assessment, computerized refraction, intraocular pressure measurement, biometry, and corneal topography examination before lens wear and at 1 month, 3 months, and 6 months after lens wear in the pediatric ophthalmology clinic.
Leveraging neural plasticity for the treatment of amblyopia.
Surv Ophthalmol
September 2024
Department of Psychology and Neuroscience, Dalhousie University, Halifax, NS, Canada.
Amblyopia is a form of visual cortical impairment that arises from abnormal visual experience early in life. Most often, amblyopia is a unilateral visual impairment that can develop as a result of strabismus, anisometropia, or a combination of these conditions that result in discordant binocular experience. Characterized by reduced visual acuity and impaired binocular function, amblyopia places a substantial burden on the developing child.
View Article and Find Full Text PDFEffective Decrease in Myopia Progression With Two Mechanisms of Management.
J Pediatr Ophthalmol Strabismus
May 2024
Purpose: To ascertain the effectiveness of 0.01% atropine treatment to inhibit myopia progression and the possible additive potency with peripheral defocus contact lenses over 3 years and the rebound effect 1 year after cessation of treatment.
Methods: This prospective study included 127 children aged 8 to 5 years, divided into three treatment groups: 0.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!