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Staging at Diagnosis and Survival of Hematologic Neoplasms in Children and Adolescents in Mato Grosso, Brazil: A Population-based Study.
Asian Pac J Cancer Prev
January 2025
Objective: To apply the Toronto Childhood Cancer Staging Guidelines (TG) and Estimate the Observed Survival Probabilities for Pediatric Patients with Leukemia and Lymphoma.
Methods: Staging at diagnosis was conducted according to tier 2 of the TG. The study cohort included patients aged 0 -19 years from the Population-Based Cancer Registry (PBCR) of Mato Grosso, diagnosed with leukemia and lymphoma between 2008 and 2017, with follow-up until December 31, 2022.
Regular Use of Oral Nonsteroidal Anti-inflammatory Drugs in a Population of Polish Seniors: Findings from the PolSenior2 Cross-Sectional Survey.
Drugs Aging
January 2025
Department of Preventive Medicine and Education, Medical University of Gdansk, Gdańsk, Poland.
Introduction: Older adults represent a growing proportion of the general population. Nonsteroidal anti-inflammatory drugs (NSAIDs) constitute a group of medicines that are both necessary, owing to their anti-inflammatory, analgesic, and cardioprotective abilities, and potentially harmful, owing to their side effects.
Objectives: This study provides a comprehensive analysis of NSAID usage patterns among Polish adults aged 60 years and older.
The bioavailability and blood levels of low-dose rapamycin for longevity in real-world cohorts of normative aging individuals.
Geroscience
January 2025
AgelessRx, Ann Arbor, MI, USA.
Rapamycin, also known as sirolimus, has demonstrated great potential for application in longevity medicine. However, the dynamics of low-dose rapamycin bioavailability, and any differences in bioavailability for different formulations (e.g.
View Article and Find Full Text PDFEvaluating and Comparing the Content Coverage of Quality Measure Sets from Israel, the United States, and the United Kingdom.
J Gen Intern Med
January 2025
Braun School of Public Health and Community Medicine, Hadassah Medical Organization, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Background: Quality of care can be measured in several dimensions: different clinical disciplines, structures/processes/outcomes of care (SPO), and also different domains of quality (effectiveness, safety, care coordination, patient-centeredness, efficiency, timeliness, and community/population health). To our knowledge, no previous study has compared different sets of performance measures in terms of how well they cover these different aspects of quality.
Objective: Compare the content coverage of major quality measure sets from Israel, the US, and the UK.
Evaluating the accuracy of impaired skin integrity in critically ill patients: Key characteristics and clinical implications.
Int J Nurs Knowl
January 2025
Graduate Program in Nursing, Federal University of Ceará, Fortaleza, Brazil.
Objective: To evaluate the accuracy of the defining characteristics of the nursing diagnosis Impaired skin integrity (00046) in patients admitted to intensive care units (ICUs).
Methods: A cross-sectional diagnostic accuracy study was conducted with 105 adult patients admitted to an ICU. A latent class model with random effects was used to test the sensitivity and specificity of the defining characteristics investigated.
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