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The neuroprotective role of volatile oils: insights into chemical profiles, characteristics, neurochemical mechanisms, and preclinical studies in Alzheimer's disease.
Inflammopharmacology
January 2025
Department of Community Medicine, Vidhyadeep Homoeopathic Medical College and Research Centre, Vidhyadeep University, Anita, Surat, Gujarat, 394110, India.
Volatile oils (VOs), synonymously termed essential oils (EOs), are highly hydrophobic liquids obtained from aromatic plants, containing diverse organic compounds for example terpenes and terpenoids. These oils exhibit significant neuroprotective properties, containing antioxidant, anti-inflammatory, anti-apoptotic, glutamate activation, cholinesterase inhibitory action, and anti-protein aggregatory action, making them potential therapeutic agents in managing neurodegenerative diseases (NDs). VOs regulate glutamate activation, enhance synaptic plasticity, and inhibit oxidative stress through the stimulation of antioxidant enzymes.
View Article and Find Full Text PDFWater triggered injectable polylactic acid hydrogel based on zwitterionic sulfobetaine modification for incompressible bleeding and tissue anti-adhesion.
Mater Today Bio
February 2025
Institution of Disaster and Emergency Medicine, Tianjin University, Tianjin, 300072, China.
Massive blood loss is the main cause of prehospital trauma-related death, the development of rapid and effective hemostatic materials is imminent. Injectable hydrogels have the advantages of covering irregular bleeding sites and quickly closing the wound. However, its inherent viscosity can easily precipitate tissue adhesion and other complications.
View Article and Find Full Text PDFErlotinib-induced Perioral Lesions Resembling Scleroderma.
Acta Dermatovenerol Croat
November 2024
Constantin A. Dasanu MD, PhD, Lucy Curci Cancer Center, Eisenhower Health, 39000 Bob Hope Dr, Rancho Mirage, CA 92270 , USA;
Erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), is currently used in the therapy of several solid malignancies. This agent has been associated with several dermatological side-effects, the most common being papulo-pustular acneiform rash. Herein we describe a unique skin effect in a patient treated with erlotinib for non-small cell lung cancer.
View Article and Find Full Text PDFModulating the Interactions of Peptide-Polyphenol for Supramolecular Assembly Coatings with Controllable Kinetics and Multifunctionalities.
Adv Sci (Weinh)
January 2025
School of Ophthalmology and Optometry, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.
Polyphenols and peptides represent two fundamental building blocks in the kingdom of supramolecular assembly (SA) coatings, which have recently attracted considerable interest. Regulating the assembly kinetics of SA coatings is critical to controlling the performance of SA coatings, but this area is still in its infancy, especially in the SA coating of peptide-polyphenol. Herein, a library of oligopeptides with rich diversity, numerous polyphenols, and modulators are explored to reveal their roles in the formation and regulation of SA coating.
View Article and Find Full Text PDFMXene and cellulose nanofibers reinforced hydrogel with high strength and photothermal self-healing performances for marine antifouling.
Carbohydr Polym
January 2025
School of Materials Science and Engineering, Hainan University, Haikou 570228, China. Electronic address:
Article Synopsis
- Biological fouling poses a significant threat to the marine industry, causing damage to installations and aquaculture due to attached microorganisms and microcontaminants.
- Researchers introduced polyhexamethylene-biguanide (PHMB) and MXene into carboxylated cellulose nanofibers reinforced polyvinyl alcohol (PVA) hydrogel to create a tough, self-healing antifouling material.
- The resulting double network (DN) hydrogels demonstrate exceptional antifouling properties, remaining effective for over six months, with high toughness, anti-protein and anti-algal adhesion, and strong antibacterial activity.
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