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Chitosan nanoparticles loaded with bioactive metabolites: Preparation, characterization, and antifungal activity.
Heliyon
January 2025
Food Toxicology and Contaminants Department, National Research Centre, Egypt.
is a severe danger to worldwide maize () cultivation, due to its extreme toxicity of aflatoxins produced by the fungi, and its ability to cause economic losses while also posing a health concern to humans and animals. Among the measures that may be considered for control, applying coatings based on natural ingredients appears to be the most promising. The current work examines the antagonistic ability of bioactive metabolites added to chitosan nanoparticles against on maize kernels.
View Article and Find Full Text PDFMethanol transfer supports metabolic syntrophy between bacteria and archaea.
Nature
January 2025
Institute for Extra-Cutting-Edge Science and Technology Avant-Garde Research (X-star), Japan Agency for Marine-Earth Science and Technology (JAMSTEC), Yokosuka, Japan.
In subsurface methanogenic ecosystems, the ubiquity of methylated-compound-using archaea-methylotrophic methanogens-implies that methylated compounds have an important role in the ecology and carbon cycling of such habitats. However, the origin of these chemicals remains unclear as there are no known energy metabolisms that generate methylated compounds de novo as a major product. Here we identified an energy metabolism in the subsurface-derived thermophilic anaerobe Zhaonella formicivorans that catalyses the conversion of formate to methanol, thereby producing methanol without requiring methylated compounds as an input.
View Article and Find Full Text PDFPurification, structural characterization, and in vitro immunomodulatory activity of a low-molecular-weight polysaccharide from cultivated Chinese cordyceps.
Int J Biol Macromol
January 2025
Key Laboratory of State Administration of Traditional Chinese Medicine, Dongguan HEC Cordyceps R&D Co., Ltd., Dongguan, Guangdong 523850, China; College of Medical Imaging Laboratory and Rehabilitation, Xiangnan University, Chenzhou, Hunan 423000, China. Electronic address:
Cultivated Chinese cordyceps, an optimal substitute for the endangered wild resource, has recently been produced on a large scale. This work sought to explore the structural features and immunomodulatory activity of a novel low-molecular-weight polysaccharide (CSP1a, 15.7 kDa) isolated from cultivated Chinese cordyceps.
View Article and Find Full Text PDFBioenergetic trade-offs can reveal the path to superior microbial CO fixation pathways.
mSystems
January 2025
Department of Chemical and P. Engineering, Research and Innovation Centre on CO2 and H2 (RICH), Khalifa University, Abu Dhabi, United Arab Emirates.
A comprehensive optimization of known prokaryotic autotrophic carbon dioxide (CO) fixation pathways is presented that evaluates all their possible variants under different environmental conditions. This was achieved through a computational methodology recently developed that considers the trade-offs between energy efficiency (yield) and growth rate, allowing us to evaluate candidate metabolic modifications for microbial conversions. The results revealed the superior configurations in terms of both yield (efficiency) and rate (driving force).
View Article and Find Full Text PDFCharacterization of Allobodo yubaba sp. nov. and Novijibodo darinka gen. et sp. nov., cultivable free-living species of the phylogenetically enigmatic kinetoplastid taxon Allobodonidae.
J Eukaryot Microbiol
January 2025
Institute for Comparative Genomics, and Department of Biology, Dalhousie University, Halifax, Nova Scotia, Canada.
Kinetoplastids are a large and diverse protist group, spanning ecologically important free-living forms to medically important parasites. The taxon Allobodonidae holds an unresolved position within kinetoplastids, and the sole described species, Allobodo chlorophagus, is uncultivated, being a necrotroph/parasite of macroalgae. Here we describe Allobodo yubaba sp.
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