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Treatment of Eyelid Entropion: A Historical Review.

Ophthalmic Plast Reconstr Surg

September 2024

Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, Missouri, U.S.A.

Purpose: The purpose of this study was to review the long history of entropion, with emphasis on its significance to the specialty of ophthalmology, and the numerous methods developed to treat cicatricial and involutional forms of the condition.

Methods: An extensive medical literature review was performed, identifying publications containing information on entropion and associated conditions. Foreign language manuscripts were translated using online resources.

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Feasibility and acceptability of integrating mass distribution of azithromycin to children 1-11 months into a trachoma mass drug administration campaign to reduce child mortality in Côte d'Ivoire.

PLOS Glob Public Health

July 2024

The Côte d'Ivoire National Neglected Tropical Diseases Program (Programme National de Lutte contre les Maladies Tropicales Négligées à Chimiothérapie Préventive), Abidjan, Côte d'Ivoire.

Evidence suggests that bi-annual mass drug administration (MDA) of single-dose azithromycin to 1-11 month-old children reduces child mortality in high child-mortality settings. Several countries conduct annual MDAs to distribute azithromycin to individuals ages 6 months and older to prevent trachoma infection. This study examined the feasibility and acceptability of reaching 1-11 months-old children during a trachoma MDA in Côte d'Ivoire by extending azithromycin distribution to infants 1-5 months old during the campaign.

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Article Synopsis
  • Persistent trachoma is a significant public health issue, especially in Ethiopia, where it is defined as having a TF prevalence of ≥5% in children after multiple impact surveys.
  • A 2019 study investigated the epidemiology of Chlamydia trachomatis infection, the cause of trachoma, across seven districts with persistent cases, revealing TF prevalence between 11.8% and 36.1%.
  • Findings indicated a strong correlation between infection and households lacking latrines, suggesting that intensified intervention strategies over the next 3-5 years are essential to meet the global trachoma elimination goal by 2030.
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Article Synopsis
  • The GET initiative aims to eliminate trachoma using the SAFE strategy, which includes Surgery, Antibiotics, Facial cleanliness, and Environmental improvement, but lacks a standardized measure for facial cleanliness.
  • This study evaluated two metrics for measuring facial cleanliness among children in Tanzania: one based on the absence of ocular and nasal discharge and the other based on dirtiness graded on a facial wipe.
  • Both metrics were found to be equally reliable and effectively detected face washing behavior, although they measure different aspects of cleanliness, suggesting the choice of metric should align with specific measurement goals.
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Objectives: NTDs historically receive less attention than other diseases in the same regions. Recent gap analyses revealed notable shortcomings despite NTD elimination progress. This systematic scoping review was conducted to understand NTD control, elimination, and eradication efforts in the WHO African region over the last 30 years.

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