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Ensembles of carboxymethyl cyclodextrins on cationic liposomes as highly efficient nanocontainers for the delivery of hydrophobic compounds.
Biochim Biophys Acta Gen Subj
June 2023
Lomonosov Moscow State University, Chemistry Department, Leninskie Gory, 1-3, Moscow 119991, Russia.
The increase of payload is one of the key tasks in creation of nanocontainers for the delivery of bioactive substances (BAS). In this work the adsorption of anionic carboxymethyl cyclodextrins (CMCDs) on the surface of cationic liposomes was studied as mechanism of formation of capacious nanocontainers for the encapsulation and delivery of hydrophobic BAS. The formation and physico-chemical characteristics of complexes were studied by means of laser microelectrophoresis, dynamic light-scattering, conductometry and atomic force microscopy (AFM).
View Article and Find Full Text PDFInvestigation of a novel smart and active packaging materials: Nanoparticle-filled carrageenan-based composite films.
Carbohydr Polym
February 2023
School of Public Health, Wuhan University, Wuhan 430071, China. Electronic address:
In this study, curcumin, zein, epigallocatechin gallate (EGCG) and carrageenan were used to fabricate curcumin-zein-EGCG-carrageenan (CZEC) layer-by-layer nanoparticles. These nanoparticles were embedded within carrageenan films to form composite films with enhanced antioxidant activity and smart responses. Light scattering, micro-electrophoresis, FTIR, and SEM were used to characterize the size, charge, interactions, and morphology of CZEC nanoparticles.
View Article and Find Full Text PDFBiocompatible Nanoparticle Heteroaggregates as Stabilizers of Pickering Emulsions for Vitamin D3 Efficient Delivery.
ACS Appl Bio Mater
August 2022
Institute of Chemistry, Federal Research Centre "Komi Science Centre, Ural Branch, Russian Academy of Sciences", 48 Pervomayskaya Street, Syktyvkar 167982, Russian Federation.
Vitamin D3 deficiency is a major public health problem worldwide, and standard cholecalciferol formulations provide poor absorbability of the vitamin. Several biphasic formulas have been proposed to overcome the disadvantages in which Pickering emulsions stand out in particular. This paper describes olive oil-in-water Pickering emulsions stabilized by pseudoboehmite (AlOOH), cellulose nanocrystals (CNC), and their heterocoagulates.
View Article and Find Full Text PDFControlled delivery of quantum dots using microelectrophoresis technique: Intracellular behavior and preservation of cell viability.
Bioelectrochemistry
April 2022
Institute for Photonics and Advanced Sensing (IPAS) and School of Physical Sciences, The University of Adelaide, Adelaide, South Australia 5005, Australia; ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP), The University of Adelaide, Adelaide, South Australia 5005, Australia. Electronic address:
The use of synthetic nanomaterials as contrast agents, sensors, and drug delivery vehicles in biological research primarily requires effective approaches for intracellular delivery. Recently, the well-accepted microelectrophoresis technique has been reported to exhibit the ability to deliver nanomaterials, quantum dots (QDs) as an example, into live cells, but information about cell viability and intracellular fate of delivered nanomaterials is yet to be provided. Here we show that cell viability following microelectrophoresis of QDs is strongly correlated with the amount of delivered QDs, which can be finely controlled by tuning the ejection duration to maintain long-term cell survival.
View Article and Find Full Text PDFSynthesis and characterization of a novel composites derived from SBA-15 mesoporous silica and iron pentacarbonyl.
J Colloid Interface Sci
February 2022
Laboratory of Electrochemistry, Lublin University of Technology, Nadbystrzycka 38, 20618 Lublin, Poland. Electronic address:
Hypothesis: Fe(CO) was deposited on SBA-15 from gaseous phase and the adsorbed iron precursor was oxidized and hydrolyzed. We hypothesize that a novel method produces composites of unique and useful properties. The absence of sulfur and halides in the composites is of special importance with respect of their potential application as catalysts and catalyst supports.
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