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| http://dx.doi.org/10.1136/jcp.10.4.387 | DOI Listing |
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A review of research progress in the design history of everyday life.
Heliyon
January 2025
Tongji University, College of Design and Innovation, Shanghai, China.
The study of everyday life has garnered significant research attention in various disciplines. However, in the field of design history, the exploration of everyday life remains in its early stages. There is a need for further organization and analysis, as there is currently no comprehensive exposition on the overall research progress in this field.
View Article and Find Full Text PDFExploring the Therapeutic Role of Flavonoids Through AMPK Activation in Metabolic Syndrome: A Narrative Review.
Phytother Res
January 2025
Faculty of Pharmaceutical Science, Assam Down Town University, Guwahati, Assam, India.
Metabolic syndrome (MetS) is a cluster of interrelated metabolic abnormalities that significantly elevate the risk of cardiovascular disease, obesity, and diabetes. Flavonoids, a diverse class of bioactive polyphenolic compounds found in plant-derived foods and beverages, have garnered increasing attention as potential therapeutic agents for improving metabolic health. This review provides a comprehensive analysis of the therapeutic effects of flavonoids in the context of the MetS, with a particular focus on their modulation of the AMP-activated protein kinase (AMPK) pathway.
View Article and Find Full Text PDFRight Ventricle Function: The Role of the Forgotten Chamber in Mitral Valve Surgery.
Curr Cardiol Rep
January 2025
Division of Cardiac Surgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Background: Referred to as the "forgotten chamber," the right ventricle (RV) is now widely acknowledged as a significant factor, particularly in certain cardiovascular pathologies. Despite historically being undervalued in comparison to the left ventricle, the RV function is deemed crucial in determining patient outcomes following mitral valve (MV) surgery. In the context of MV surgery, it is important to note that the RV is highly susceptible to dysfunction before, during, and after the surgical procedure.
View Article and Find Full Text PDFUsing minimally invasive tissue sampling (MITS) and Determination of Cause of Death (DeCoDe) to establish etiologies of community respiratory deaths among Zambian infants and children.
J Pediatric Infect Dis Soc
December 2024
Bill & Melinda Gates Foundation, Seattle, WA, USA.
In low-to-middle income countries, acute lower respiratory infection (ALRI) remains the leading infectious cause of death among infants and children under 5 years old. Case-control studies based on upper respiratory sampling have informed current understandings of ALRI etiologies; in contrast, minimally-invasive tissue sampling (MITS) offers a method of directly interrogating lower respiratory tract pathogens to establish etiologic distributions. This study performed in the post-mortem setting used MITS and a Determination of Cause of Death (DeCoDe) panel to elucidate causes of fatal pneumonia in the community in Lusaka, Zambia.
View Article and Find Full Text PDFBiomarkers.
Alzheimers Dement
December 2024
Memory Clinic, Skåne University Hospital, Malmö, Sweden.
Background: A key characteristic of Alzheimer's disease (AD) is cerebral aggregation of tau. These aggregates can be quantified and localized with positron emission tomography (PET), which improves the diagnostic and prognostic work-up of AD. However, tau-PET is expensive and not available in clinical settings globally.
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