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Introduction: The technical development of ultrasound devices based on silicon chips has revolutionized ultrasound examinations, leading to the implementation of these portable handheld devices (PUD) in different medical fields. However, training on these devices is necessary to assure appropriate use and ensure valid results. While training programs for the use of conventional standard ultrasound devices (SUD) have been described, no training program for these handheld devices has been developed thus far.

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SLC1A5 is a key regulator of glutamine metabolism and a prognostic marker for aggressive luminal breast cancer.

Sci Rep

January 2025

Nottingham Breast Cancer Research Centre, Academic Unit of Translational Medical Sciences, School of Medicine, University of Nottingham, University of Nottingham Biodiscovery Institute, University Park, Nottingham, NG7 2RD, England.

Cancer cells exhibit altered metabolism, often relying on glutamine (Gln) for growth. Breast cancer (BC) is a heterogeneous disease with varying clinical outcomes. We investigated the role of the amino acid transporter SLC1A5 (ASCT2) and its association with BC subtypes and patient outcomes.

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DNA ploidy status as a predictor for malignant transformation in oral leukoplakia: a systematic review and meta-analysis.

Oral Surg Oral Med Oral Pathol Oral Radiol

January 2025

Department of Oral Pathology and Microbiology, KLE VK Institute of Dental Sciences and Hospital, Constituent Unit of KLE Academy of Higher Education and Research, Belgaum, Karnataka India.

Objective: To synthesize literature regarding determination of ploidy status in cases of oral leukoplakia (OL) with the research question: Can DNA ploidy assess malignant transformation (MT) in OL cases?

Study Design: This systematic review was registered in PROSPERO (CRD42022340184). The PECO (Population, Exposure, Comparator, and Outcome) was patients with OL, aneuploidy, diploidy, and MT in OL. Literature search databases included Scopus, PubMed, and Google Scholar.

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Purpose: The current geopolitical situation and climate changes accentuate the importance of health preparedness. The aim was to examine the in-hospital preparedness for Mass Casualty Incidents (MCI) and Major Incidents (MI) on a national level.

Method: A web-based, cross-sectional study of in-hospital preparedness for MCI/MI in Norway.

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Osteoporosis is a chronic disease that is characterized by a loss of bone density, which mainly affects the microstructure of the bones due to a decrease in bone mass, thereby making them more fragile and susceptible to fractures. Osteoporosis is currently considered one of the pandemics of the 21st century, affecting around 200 million people. Its most serious consequence is an increased risk of bone fractures, thus making osteoporosis a major cause of disability and even premature death in the elderly.

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