Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2082602 | PMC |
Publication Analysis
Top Keywords
Similar Publications
Current antibiotics for leptospirosis: Are still effective?
Heliyon
January 2025
School of Biological Sciences, Universiti Sains Malaysia, Penang, Malaysia.
Leptospirosis is a recurring zoonotic disease of global significance. Leptospirosis is curable, and antibiotics are available for its treatment. However, little is known about the effectiveness of the currently used antibiotics against different species, serovars, and strains.
View Article and Find Full Text PDFA New Beginning to the Existing Medicines; Repurposing FDA-Approved Drugs for the Neglected Re-Emerging Disease Leptospirosis.
ACS Omega
July 2024
Department of Biochemistry, ICMR Regional Medical Research Centre, Port Blair, Andaman and Nicobar Islands 744103, India.
Leptospirosis is one of the re-emerging zoonotic diseases, especially in tropical regions. Many antibiotics are used to treat leptospirosis, but there are no scientific evidence-based guidelines or systematic clinical trials for using these drugs. A bioinformatics approach was made to shortlist some Food and Drug Administration (FDA) of the United States of America-approved and currently used drugs for leptospirosis.
View Article and Find Full Text PDFA clinical pilot study for the detection of sphingomyelinase in leptospirosis patient's urine at tertiary care hospital.
Heliyon
October 2023
Department of Microbiology, Yenepoya Medical College, Yenepoya (Deemed to be University), Deralakatte, Mangalore, 575 018, India.
Purpose: Leptospirosis is a perplexing mystification for many clinicians. Clinically often underdiagnosed due to lack of a rapid, sensitive, and specific diagnostic test. Currently available diagnostic tests have their own limitations; therefore, monitoring biomarkers that contribute an essential role in pathogenesis is crucial.
View Article and Find Full Text PDFStrong Evidence of the Role of Donkeys in the Epidemiology of spp. in Semiarid Conditions.
Microorganisms
July 2023
Centro de Saúde Tecnologia Rural (CSTR), Universidade Federal de Campina Grande (UFCG), Av. Universitária, s/n, Santa Cecília, Patos 58708-110, PB, Brazil.
Donkeys () are historically known for their close relationship to humanity, which raises the need to study zoonotic diseases that affect them. In this perspective, leptospirosis stands out as a disease with an economic and public health impact, and its occurrence is facilitated in times of higher rainfall indexes, especially in large urban centers. In view of the scarcity of information about leptospirosis in donkeys, the objective of this study was to detect the presence of spp.
View Article and Find Full Text PDFPrevalence of anti-leptospiral IgM and detection of pathogenic Leptospira species DNA in neonates presenting with clinical sepsis in Southwestern Uganda.
Eur J Med Res
December 2022
Department of Medical Microbiology, Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Background: Leptospirosis is an emerging neglected zoonotic disease that presents with nonspecific signs/symptoms and it can be mistaken for other diseases. Owing to limited diagnostic capacity and unawareness, the data on human leptospirosis particularly in neonates are scarce in many sub-Saharan countries. It has been underreported hindering preventive and control measures in place.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!