Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Still a long way to go, the potential of ChatGPT in personalized dietary prescription, from a perspective of a clinical dietitian.
J Ren Nutr
March 2025
Department of Clinical Nutrition, West China Hospital, Sichuan University, Chengdu, China. Electronic address:
Background: Prominent large language models, such as OpenAI's ChatGPT, have shown promising implementation in the field of nutrition. Special care should be taken when using ChatGPT to prescribe protein restricted diets for kidney impaired patients. The objective of the current study is to simulate a chronic kidney disease (CKD) patient and evaluate the capabilities of ChatGPT in the context of dietary prescription, with a focus on protein contents of the diet.
View Article and Find Full Text PDFPitavastatin-induced cholesterol deficiency elevates serum biomarkers associated with statin-related adverse effects in rats.
Cardiovasc Endocrinol Metab
June 2025
Department of Medical Sciences, Faculty of Medicine, Qom Medical Sciences, Islamic Azad University, Qom, Iran.
Background: Statins are prescribed to manage hypercholesterolemia. While effective, these medications are associated with adverse effects, particularly myopathy. Cholesterol is essential for muscle function, and its depletion - especially by lipophilic statins - may contribute to muscle damage.
View Article and Find Full Text PDFSafety and Efficacy of DTX401, an AAV8-Mediated Liver-Directed Gene Therapy, in Adults With Glycogen Storage Disease Type I a (GSDIa).
J Inherit Metab Dis
March 2025
Ultragenyx Pharmaceutical Inc., Novato, California, USA.
Glycogen storage disease type Ia (GSDIa) is a rare, life-threatening, inherited carbohydrate metabolism disorder caused by glucose-6-phosphatase (G6Pase) deficiency, which is essential for glycogenolysis and gluconeogenesis. GSDIa management includes a strict medically prescribed diet that typically includes daily uncooked cornstarch doses, including overnight, to maintain euglycemia. DTX401 is an investigational adeno-associated virus serotype 8 vector expressing the human G6PC1 gene that encodes G6Pase.
View Article and Find Full Text PDFAlterations of valsartan pharmacokinetics in a rodent model of metabolic dysfunction-associated steatohepatitis.
Drug Metab Dispos
January 2025
College of Pharmacy, Department of Pharmacology & Toxicology, The University of Arizona, Tucson, Arizona. Electronic address:
Valsartan (VAL) is commonly prescribed for patients with cardiovascular disease (CVD) to lower blood pressure, reduce heart failure risk, and prevent heart attacks or strokes by blocking the effects of angiotensin II. Many patients with CVD also suffer from metabolic dysfunction-associated steatohepatitis (MASH), which disrupts several xenobiotic transporters, affecting the pharmacokinetics of numerous drugs. Medications used in patients to treat comorbidities associated with MASH may be subject to this altered disposition and potential toxicity.
View Article and Find Full Text PDFEffectiveness of patient education on adherence to treatment regimen and quality of life in hemodialysis patients: a systematic review and meta-analysis.
Minerva Urol Nephrol
March 2025
Shifa College of Nursing, Shifa Tameer- e- Millat University, Sector H-8/4 Islamabad, Pakistan.
Introduction: Hemodialysis constitutes a protracted therapeutic intervention for renal failure, characterized by symptoms that exert a considerable toll on quality of life owing to their intensity and frequent recurrence. Patient education and engagement has been shown to enhance adherence, thereby improving treatment effectiveness and quality of life. The objective of this systematic review was to assess the effectiveness of patient education on improving adherence to treatment and enhancing quality of life among individuals undergoing hemodialysis.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!