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Production and characterization of sophorolipid under yeast-mediated submerged fermentation utilizing Agro-industrial waste.
Curr Res Microb Sci
December 2024
Material Resource Efficiency Division, CSIR-Indian Institute of Petroleum, Mohkampur, Dehradun 248005, Uttarakhand, India.
The challenges of pollution and agro-industrial waste management have led to the development of bioconversion techniques to transform these wastes into valuable products. This has increased the focus on the sustainable and cost-efficient production of biosurfactants from agro-industrial waste. Hence, the present study investigates the production of sophorolipid biosurfactants using the yeast strain IIPL32 under submerged fermentation, employing sugarcane bagasse hydrolysate-a renewable, low-cost agro-industrial waste as the feedstock.
View Article and Find Full Text PDFThe Diagnostic Value of Bile Acids and Amino Acids in Differentiating Acute Coronary Syndromes.
Int J Gen Med
January 2025
Post Graduate School of Jinzhou Medical University, Jinzhou, Liaoning, People's Republic of China.
Purpose: Acute coronary syndrome (ACS), comprising unstable angina and acute myocardial infarction, is the most dangerous and fatal form of coronary heart disease. This study evaluates serum bile acids (BAs) and amino acids (AAs) as potential predictors of AMI in UA patients.
Patients And Methods: A total of 72 Non-Coronary Artery Disease (NCAD) patients, 157 UA patients, and 79 AMI patients were analyzed.
Rapid screening of pottery lipid residue profile via comprehensive two-dimensional gas chromatography.
Anal Chim Acta
February 2025
Department of Archaeology and Anthropology, School of Humanities, University of Chinese Academy of Sciences, 100049, Beijing, China. Electronic address:
Background: Pottery lipid residue analysis has been extensively practiced worldwide as an important part of archaeometry studies, but in some cases, the complexity of archaeological residue cannot be fully revealed by one-dimensional gas chromatography (1D GC) separation. Although the development of comprehensive two-dimensional gas chromatography (GCxGC) has offered another way to achieve better separation and higher resolution, GCxGC separation has rarely been applied to pottery residue analysis. Clearly, GCxGC separation needs to be explored to examine and scrutinize the complexity of pottery lipid residue profile as well as rapid data treatment workflow.
View Article and Find Full Text PDFInvestigating residual trace metals in recombinant monoclonal antibodies to facilitate drug development with LC-UV-ICPMS-HRMS.
Anal Chim Acta
February 2025
Regeneron Pharmaceuticals, Inc., Tarrytown, NY, 10591-6707, USA.
Background: The biopharmaceutical industry is increasingly interested in the analysis of trace metals due to their significant impact on product quality and drug safety. Certain metals can potentially accelerate the formation of degradants or aggregates in biotherapeutic proteins, leading to drug product quality concerns. A better understanding of metal-mAb interactions would aid in the development of purification processes and formulations, thereby ensuring better drug quality and safety.
View Article and Find Full Text PDFGlobal retention model based on multisample system parameters for optimising chromatographic fingerprints of medicinal plants.
Anal Chim Acta
February 2025
Department of Analytical Chemistry, Faculty of Chemistry, Universitat de València, C/ Dr. Moliner 50, 46100, Burjassot, Spain. Electronic address:
Background: Developing analytical methods for Traditional Medicine products by liquid chromatography is challenging due to their chemical complexity and the lack of analytical standards for numerous, unidentified constituents. Regulatory agencies recommend chromatographic fingerprint analysis for quality evaluation, relying on peak detection to ensure resolution. Conventional modelling struggles to optimise experimental conditions for such complex samples.
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