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Once-Weekly Insulin: A Breakthrough in Diabetes Management or an Unresolved Challenge?
Br J Hosp Med (Lond)
January 2025
Department of Medicine, Rawalpindi Medical University, Rawalpindi, Pakistan.
The advent of once-weekly insulin icodec is a promising development in the care of individuals with diabetes. These once-weekly formulations aimed to improve patient adherence and quality of life for patients who find daily injection administration challenging. Insulin icodec has demonstrated comparable glycemic control to conventionally used daily basal insulins, such as insulin glargine and degludec, in the ONWARDS clinical trials.
View Article and Find Full Text PDFSmartphone-Based Experimental Analysis of Rainfall Effects on LTE Signal Indicators.
Sensors (Basel)
January 2025
Global Big Data Technologies Centre (GBDTC), University of Technology Sydney (UTS), Sydney, NSW 2007, Australia.
This work investigates the impact of rainfall on cellular communication links, leveraging smartphone-collected measurements. While existing studies primarily focus on line-of-sight (LoS) microwave propagation environments, this work explores the impact of rainfall on typical signal metrics over cellular links when the LoS path is not guaranteed. We examine both small-scale and large-scale variations in signal measurements across dry and rainy days, considering diverse locations and time windows.
View Article and Find Full Text PDFVariations in land surface temperature increase in South-East Asian Cities.
Environ Monit Assess
January 2025
Mathematics Department, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh, Indonesia.
Climate change and global warming are terms used to describe the variation in the Earth's mean temperature as a result of human activities contributing to the formation of urban heat islands (UHI). One method for determining the temperature of a region is the land surface temperature (LST). The study of LSTs is important and closely related to climate change, as is the provision of convenient living and working conditions in cities, which support economic growth.
View Article and Find Full Text PDFImpact of disease cyclicity on quality-of-life impairment-A mixed method explanatory study.
JAAD Int
February 2025
Division of Dermatology, Department of Medicine, National University Healthcare System, Singapore.
Background: Disease cyclicity, a composite measure of unpredictable and daily fluctuations of symptoms, strongly predicts quality-of-life (QoL) impairment.
Objective: To explore the mechanisms by which cyclicity impacts QoL.
Methods: 1:1 semi-structured interviews were conducted and qualitatively analyzed using grounded theory.
Diurnal and daily fluctuations in levels of the urinary oxidative stress marker 8-hydroxyguanosine in spot urine samples.
Genes Environ
January 2025
Department of Environmental Oncology, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8555, Japan.
Background: Urinary 8-hydroxyguanosine (8-OHGuo) levels serve as a biomarker for oxidative stress and hydroxyl radical-induced RNA damage. Evaluating the diurnal and daily fluctuations in urinary 8-OHGuo excretion levels is essential for understanding its implications. However, research in this area remains limited.
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