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How SNARE proteins generate force to fuse membranes.
Biophys J
January 2025
Department of Chemical Engineering, Columbia University, New York, NY 10027. Electronic address:
Membrane fusion is central to fundamental cellular processes such as exocytosis, when an intracellular machinery fuses membrane-enclosed vesicles to the plasma membrane for contents release. The core machinery components are the SNARE proteins. SNARE complexation pulls the membranes together, but the fusion mechanism remains unclear.
View Article and Find Full Text PDFNontraumatic right diaphragmatic hernia with malrotated left liver lobe incarceration: An unusual case report with literature review.
Radiol Case Rep
March 2025
Department of Radiology, Mohammed Vth Military hospital, Ryad street, 10010 Rabat, Morocco.
Diaphragmatic hernia is an unusual finding, especially in emergency settings and in the absence of trauma. Imaging plays a crucial role, with various CT signs of diaphragmatic rupture having been described, including the "dangling diaphragm," "absent diaphragm," "collar sign," "hump sign," "fascia sign," and "dependent viscera sign". We report an unusual case of a 53-year-old woman who presented with exertional dyspnea and asthenia.
View Article and Find Full Text PDFDiaphragmatic Rupture in the Postpartum Period.
Cureus
December 2024
General Surgery, Ibn Rochd University Hospital/Hassan II University, Casablanca, MAR.
Diaphragmatic rupture during labor is an exceptionally rare condition, with a limited number of cases reported in the literature. A recent review underscores the rarity of this complication and emphasizes the associated challenges in diagnosis and management. This case report presents a postpartum diaphragmatic rupture, focusing on the diagnostic and therapeutic challenges it poses, particularly in the context of unsupervised deliveries.
View Article and Find Full Text PDFA review of literature of a functional, congenital intrathoracic kidney.
J Cardiothorac Surg
January 2025
Internal Medicine, University of Arkansas for Medical Sciences - Northwest, Fayetteville, USA.
Introduction: The rarest form of renal ectopia, the thoracic kidney, has been documented in only about 200 cases worldwide. There are four recognized causes of congenital thoracic renal ectopia: renal ectopia with an intact diaphragm, diaphragmatic eventration, diaphragmatic hernia, and traumatic diaphragmatic rupture. This condition often presents as an incidental finding in asymptomatic patients.
View Article and Find Full Text PDFGastrointestinal perforation caused by displaced contraceptive device: a case report.
Pan Afr Med J
December 2024
Department of Visceral Surgery, Fattouma Bourguiba Hospital, Monastir University, Monastir, Tunisia.
The intrauterine device (IUD) is a widely utilized contraceptive method. In cases of uterine rupture, an IUD can migrate to the intra-abdominal or pelvic cavity, leading to various complications such as gastrointestinal perforation. The aim of this study was to report a case of a 29-year-old woman presented with acute left lumber pain.
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