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Lesion development in white-tailed deer (Odocoileus virginianus) experimentally infected with Mycobacterium bovis.
Vet Pathol
May 2002
National Animal Disease Center, Agricultural Research Service, US Department of Agriculture, Ames, IA 50010, USA.
The recent discovery of tuberculosis in free-living white-tailed deer in northeastern Michigan underscores the need for increased understanding of the pathogenesis of tuberculosis in wildlife species. To investigate lesion development in white-tailed deer, 32 deer were experimentally infected by intratonsilar instillation of 300 colony-forming units of Mycobacterium bovis. Three deer each were euthanatized and examined at days 15, 28, 42, and 56 after inoculation, and five deer each were euthanatized and examined at days 89, 180, 262, and 328 after inoculation.
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