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Novel Amazonian Ceratomyxa species (Cnidaria: Myxozoa) with amoeboid plasmodial motility.

Microb Pathog

February 2025

Universidade Federal de São Paulo, Instituto de Ciências Ambientais, Químicas e Farmacêuticas, Diadema, São Paulo, CEP 09972-270, Brazil; Universidade Estadual de Campinas, Instituto de Biologia, Campinas, CEP 13083-862, Brazil.

Myxosporeans are a diverse group of cnidarian endoparasites of aquatic animals, with more than 2600 described species. The genus Ceratomyxa includes some 270 species that are mostly coelozoic and infect the gall bladders of mainly marine fish. During our survey in Tapajós River in the Brazilian Amazon, two Ceratomyxa species were discovered in the gallbladders of the anostomid fishes Schyzodon fasciatus and Schyzodon vittatus.

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Two invasive hemipteran adelgids cause widespread damage to North American conifers. (the hemlock woolly adelgid) has decimated and (the Eastern and Carolina hemlocks, respectively). was introduced from East Asia and reproduces parthenogenetically in North America, where it can kill trees rapidly.

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The SIMPL'HIV study investigated whether switching to dolutegravir (DTG) + emtricitabine (FTC) was noninferior to continuing combined antiretroviral therapy for maintaining HIV-1 suppression at 144 weeks. The study demonstrated that viral suppression, CD4 gains, adverse events, quality of life, and patient satisfaction were comparable between groups, confirming DTG + FTC's safety and efficacy for long-term management of HIV-1 infection.

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Article Synopsis
  • Phospholamban (PLN) is a protein that plays a crucial role in heart muscle function by regulating calcium levels, and a specific mutation (R14Δ-PLN) leads to severe heart muscle disease that doesn't respond well to standard treatments.
  • Researchers are using a technique called complexome profiling (CP) to analyze how this mutation affects protein complexes in the hearts of mice, but existing methods face challenges because most data is based on cancer cells rather than heart cells.
  • To overcome this, a new analysis approach named PERCOM was developed, which identified 296 proteins with altered behaviors in mutant heart tissue, particularly affecting mitochondrial and intercalated disk supercomplexes.
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Article Synopsis
  • * A 64-year-old woman was treated for CAP after presenting with abdominal pain and gastrointestinal bleeding, with imaging confirming the diagnosis.
  • * Successful management involved angioembolization followed by cholecystectomy, highlighting the need for early detection and intervention in cases of CAP associated with acute cholecystitis.
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