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The Unique Roles of Ion Channels in Pluripotent Stem Cells in Response to Biological Stimuli.
Biology (Basel)
December 2024
School of Pharmacy at Fukuoka, International University of Health and Welfare, Enokizu 137-1, Okawa 831-8501, Fukuoka, Japan.
Ion channels are essential for mineral ion homeostasis in mammalian cells, and these are activated or inhibited by environmental stimuli such as heat, cold, mechanical, acidic, or basic stresses. These expressions and functions are quite diverse between cell types. The function and importance of ion channels are well-studied in neurons and cardiac cells, while those functions in pluripotent stem cells (PSCs) were not fully understood.
View Article and Find Full Text PDFOsteogenic Induction Activity of Magnesium Chloride on Human Periodontal Ligament Stem Cells.
Int Dent J
December 2024
Center of Excellence for Dental Stem Cell Biology, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand; Department of Anatomy, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand. Electronic address:
Objectives: Periodontal ligament stem cells (PDLSCs) are promising for regenerative therapies due to their self-renewal and multilineage differentiation, essential for periodontal tissue repair. Although magnesium plays a vital role in bone metabolism, its specific effects on PDLSCs and potential applications in regeneration are unclear. This study aimed to investigate the effects of magnesium chloride (MgCl₂) on the proliferation and osteogenic differentiation of human PDLSCs (hPDLSCs).
View Article and Find Full Text PDFPre-Grafting Exposure to Root-Promoting Compounds Improves Top-Grafting Performance of Citrus Trees.
Plants (Basel)
November 2024
Center of Molecular Ecophysiology (CMEP), College of Resources and Environment, Southwest University, Chongqing 400716, China.
Top grafting is an efficient and practical technique for the renewal and rejuvenation of citrus trees in old orchards. However, root death after top grafting restricts plant growth and canopy reconstruction. Thus, applications of rooting promotion substances before citrus top grafting may increase the amount and activity of roots, thereby enhancing top-grafted plant performance.
View Article and Find Full Text PDFPeripheral Lysosomal Positioning in Inflamed Odontoblasts Facilitates Mineralization.
J Endod
November 2024
State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, China. Electronic address:
Introduction: Odontoblasts, terminally differentiated dentin-producing cells, critically rely on lysosomal functions for intracellular recycling and renewal. Beyond their traditional degradative role, lysosomes actively orchestrate cellular responses to external stimuli through precise and rapid intracellular trafficking and positioning. This study aimed to explore the influence of lysosomal positioning on odontoblast mineralization and the underlying mechanisms implicated in carious inflammation.
View Article and Find Full Text PDFExperimental Research on the Performance of Recycled Waste Concrete Powder (RWCP) on Concrete.
Materials (Basel)
October 2024
School of Automotive and Traffic Engineering, Wuhan University of Science and Technology, Wuhan 430071, China.
Waste concrete is a large amount of solid waste produced in the process of urban construction and renewal in China. Its resource utilization is of great significance for saving mineral resources and improving urban environmental quality. The present study was designed to investigate the effects of mechanical grinding time on the particle size distribution and activity of recycled waste concrete powder (RWCP).
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