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Transcriptome and translatome profiling of Col-0 and grp7grp8 under ABA treatment in Arabidopsis.
Sci Data
December 2024
Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.
Abscisic acid (ABA) is a crucial phytohormone that regulates plant growth and stress responses. While substantial knowledge exists about transcriptional regulation, the molecular mechanisms underlying ABA-triggered translational regulation remain unclear. Recent advances in deep sequencing of ribosome footprints (Ribo-seq) enable the mapping and quantification of mRNA translation efficiency.
View Article and Find Full Text PDFBMT: A Cross-Validated ThinPrep Pap Cervical Cytology Dataset for Machine Learning Model Training and Validation.
Sci Data
December 2024
Department of Pathology and Laboratory Medicine, Alpert Medical School, Brown University, Providence, RI, 02912, USA.
In the past several years, a few cervical Pap smear datasets have been published for use in clinical training. However, most publicly available datasets consist of pre-segmented single cell images, contain on-image annotations that must be manually edited out, or are prepared using the conventional Pap smear method. Multicellular liquid Pap image datasets are a more accurate reflection of current cervical screening techniques.
View Article and Find Full Text PDFscRNA + BCR-seq identifies proportions and characteristics of dual BCR B cells in the peritoneal cavity of mice and peripheral blood of healthy human donors across different ages.
Immun Ageing
December 2024
Department of Immunology, Center of Immuno-molecular Engineering, Innovation & Practice Base for Graduate Students Education, Zunyi Medical University, Zunyi, China.
The increased incidence of inflammatory diseases, infectious diseases, autoimmune disorders, and tumors in elderly individuals is closely associated with several well-established features of immunosenescence, including reduced B cell genesis and dampened immune responses. Recent studies have highlighted the critical role of dual receptor lymphocytes in tumors and autoimmune diseases. This study utilized shared data generated through scRNA-seq + scBCR-seq technology to investigate the presence of dual receptor-expressing B cells in the peritoneum of mouse and peripheral blood of healthy volunteers, and whether there are age-related differences in dual receptor B cell populations.
View Article and Find Full Text PDFFAIR Data Cube, a FAIR data infrastructure for integrated multi-omics data analysis.
J Biomed Semantics
December 2024
Medical BioSciences Department, Radboud University Medical Center, Nijmegen, The Netherlands.
Motivation: We are witnessing an enormous growth in the amount of molecular profiling (-omics) data. The integration of multi-omics data is challenging. Moreover, human multi-omics data may be privacy-sensitive and can be misused to de-anonymize and (re-)identify individuals.
View Article and Find Full Text PDFThree Years of Stable Water Isotope Data of Daily Rain Samples Collected from Three Geomorphic Regions of India.
Sci Data
December 2024
Centre for Climate Change Research, Indian Institute of Tropical Meteorology, Ministry of Earth Sciences, Pune, India.
High-frequency precipitation (solid/liquid) isotope datasets are useful for identification of moisture sources and various dynamical and thermodynamical processes controlling precipitation formation. Here, we report three-year (2019-2021) daily rain isotope (both oxygen, δO hereafter, and hydrogen, δH, hereafter) datasets from three unique locations in India during the Indian Summer Monsoon (ISM). The locations are- (1) Port Blair- an island situated in the Bay of Bengal (BoB); (2) Mahabaleshwar, located at the crest of the Western Ghats Mountain; and (3) Tezpur, in northeast India, situated close to a dense forest.
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