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Introduction: is a formidable pathogen that poses a significant threat to immunocompromised and might cause rare atypical forms of the disease especially complicated with coinfection.

Case: We present a case of a patient with meningoencephalitis, endocarditis, sepsis, and osteomyelitis, highlighting the complexities of managing disseminated polymicrobial infection. A 64-year-old female with multiple myeloma treated with chemotherapy presented with fever, altered mental status, nausea, and diarrhea to the emergency department.

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Non-Classical Complications of Adult-Onset Still's Disease: A Multicenter Spanish Study.

J Clin Med

January 2025

Department of Pediatric Rheumatology, Institut de Recerca Sant Joan de Déu, Hospital Sant Joan de Déu, Universitat de Barcelona, 08950 Barcelona, Spain.

To investigate the prevalence and clinical spectrum of atypical or non-classical complications in adult-onset Still's disease (AOSD) beyond macrophage activation syndrome (MAS) and to identify factors linked to their occurrence. Multicenter cross-sectional study of AODS cases included in the Spanish registry on Still's disease. This study included 107 patients (67% women), of whom 64 (59.

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Infective endocarditis commonly presents with fever, malaise, fatigue, and chest pain. However, this case report details an atypical presentation of infective endocarditis when a 63-year-old male patient was referred by his general practitioner to the emergency department with shortness of breath and substantial weight loss to investigate his symptomatic anemia. His initial assessments revealed severe iron deficiency anemia without any gastrointestinal or any other source of bleeding.

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Relevance of cardiac imaging in the evolving landscape of infective endocarditis management.

Ther Adv Cardiovasc Dis

December 2024

Section of Cardiovascular Imaging, Robert and Suzanne Tomsich Department of Cardiovascular Medicine, Sydell and Arnold Family Heart, Vascular, and Thoracic Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk J1-5, Cleveland, OH 44195, USA.

Infective endocarditis (IE) is an increasingly recognized condition with high morbidity. Patients with atypical symptoms, culture-negative infections, and prosthetic cardiac devices and implants represent challenging populations to evaluate and manage. Recent major society guidelines have recommended the appropriate incorporation of multimodality imaging in the evaluation of these more complex IE cases.

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Vasculitis can be challenging to diagnose, especially when vessels of multiple sizes are affected and manifestations do not classically fit into defined rheumatic disease entities. We present the case of a 58-year-old Caucasian woman who presented with headache and altered mental status, with subsequent left-sided hemiparesis and hemispatial neglect eight days after a dental procedure. She was found to have extensive multi-focal ischemic infarctions secondary to vasculitis affecting multiple intracranial blood vessels.

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