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Current diagnostic methods for dyslexia primarily rely on traditional paper-and-pencil tasks. Advanced technological approaches, including eye-tracking and artificial intelligence (AI), offer enhanced diagnostic capabilities. In this paper, we bridge the gap between scientific and diagnostic concepts by proposing a novel dyslexia detection method, called INSIGHT, which combines a visualisation phase and a neural network-based classification phase.

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Background: Perception-related errors comprise most diagnostic mistakes in radiology. To mitigate this problem, radiologists use personalized and high-dimensional visual search strategies, otherwise known as search patterns. Qualitative descriptions of these search patterns, which involve the physician verbalizing or annotating the order he or she analyzes the image, can be unreliable due to discrepancies in what is reported versus the actual visual patterns.

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Systematic Reviews on the Management of Xerostomia and Hyposalivation-An Umbrella Review.

Gerodontology

January 2025

School of Dentistry, Universidade Comunitária da Região de Chapecó-Unochapecó, Área de Ciências da Saúde, Chapecó, Santa Catarina, Brazil.

Introduction: Dry mouth is moderately prevalent in the older population. Pharmacological and non-pharmacological alternatives have been assessed to manage its manifestation. This umbrella review synthesised the evidence on approaches to managing xerostomia and hyposalivation.

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Punctuational evolution is pervasive in distal site metastatic colonization.

Proc Biol Sci

January 2025

Cancer Ecology Center, The Brady Urological Institute, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.

The evolution of metastasis, the spread of cancer to distal sites within the body, represents a lethal stage of cancer progression. Yet, the evolutionary dynamics that shape the emergence of metastatic disease remain unresolved. Here, using single-cell lineage tracing data in combination with phylogenetic statistical methods, we show that the evolutionary trajectory of metastatic disease is littered with bursts of rapid molecular change as new cellular subpopulations appear, a pattern known as punctuational evolution.

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Introduction: Learning style denotes a learner's approach to acquiring, processing, interpreting, organizing, and contemplating information. VARK, formulated by Fleming and Mills (1992), assesses learning styles: Visual (V), Aural (A), Reading/Writing (R), and Kinesthetic (K). Visual learners prefer observing; Aural learners favor listening to lectures; Reading/Writing learners engage through texts and notes; Kinesthetic learners benefit from tactile activities.

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