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Functional Radiosurgery in the Management of Cancer Pain: A Comprehensive Review.
Hematol Oncol Clin North Am
January 2025
Department of Radiation Oncology, University of Miami, Miami, OH, USA.
Functional radiosurgery is a minimally invasive and highly precise approach to managing refractory cancer pain, offering targeted interventions for both nociceptive and neuropathic pain mechanisms. By focusing on key neuroanatomical targets, such as the thalamus, cingulate cortex, pituitary gland, celiac plexus, and dorsal root ganglia, functional radiosurgery provides effective relief for complex pain syndromes that are often unresponsive to conventional therapies. Advances in imaging and treatment delivery have enhanced the safety and efficacy of these techniques, allowing clinicians to tailor interventions to individual patients.
View Article and Find Full Text PDFSevere hypoglycemia in a diabetic patient with pituitary apoplexy: a case report.
J Med Case Rep
August 2024
Debre Tabor Comprehensive Specialized Hospital, Debre Tabor, Ethiopia.
Article Synopsis
- Hypoglycemia is frequently seen in diabetic patients, often caused by medications, but can also stem from other health issues, as demonstrated by a case of acute hypopituitarism due to pituitary apoplexy.
- A 45-year-old male diabetic patient presented with severe hypoglycemia and changes in mental state, leading to the discovery of a pituitary macroadenoma with hemorrhage through brain imaging.
- Management should consider the potential for rare causes like hypopituitarism when patients with diabetes exhibit severe hypoglycemia and altered mentation, indicating possible cortisol deficiency.
Acromegaly in humans and cats: Pathophysiological, clinical and management resemblances and differences.
Growth Horm IGF Res
June 2024
Pituitary Tumor Unit, Endocrinology Department, Hospital CUF Descobertas, Lisbon, Portugal; Faculdade de Medicina, Universidade Católica Portuguesa, Lisbon, Portugal. Electronic address:
Article Synopsis
- Acromegaly is a disorder caused by excess growth hormone (GH) and insulin-like growth factor-1 (IGF-1), leading to distinct physical changes and various health complications in both humans and cats.
- A literature review highlighted similarities and differences in how acromegaly manifests in these species, including craniofacial changes, joint issues, and cardiometabolic risks.
- Both species experience growth-related problems and associated diseases, but unique symptoms like human-specific skin conditions and different physical changes in cats distinguish their presentations.
In Reply to the Letter to the Editor Regarding "Risk Factors Related to Transient Diabetes Insipidus Development Following Transsphenoidal Pituitary Adenoma Resection: A Multicentric Study".
World Neurosurg
May 2024
Department of Neurosurgery, LINT, School of Medicine, National University of Tucuman, Tucuman, Argentina.
Low libido despite high normal testosterone levels in a male with an FSH-secreting pituitary macroadenoma.
Endocrinol Diabetes Metab Case Rep
January 2024
Department of Diabetes and Endocrinology, University Hospital Aintree, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
Article Synopsis
- Functioning gonadotroph adenomas are rare tumors that secrete excess follicle-stimulating hormone (FSH) and often lead to sexual dysfunction and other symptoms before being diagnosed.
- A case study highlighted a 37-year-old male with FSH-secreting macroadenoma who experienced sexual difficulties, testicular issues, and later headaches and visual problems, ultimately diagnosed through imaging and hormonal tests.
- The patient underwent successful surgery, resulting in significant improvement in hormone levels and symptoms, underlining the importance of considering rare pituitary disorders in patients with atypical hypogonadal symptoms.
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