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The elimination of Trypanosoma brucei gambiense? Challenges of reservoir hosts and transmission cycles: Expect the unexpected.
Parasite Epidemiol Control
August 2019
Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.
The World Health Organisation has set the goal for elimination of Human African Trypanosomiasis (HAT), caused by (gHAT), as a public health problem for 2020 and for the total interruption of transmission to humans for 2030. Targeting human carriers and potential animal reservoir infections will be critical to achieving this ambitious goal. However, there is continuing debate regarding the significance of reservoir host animals, wild and domestic, in different epidemiological contexts, whilst the extent and duration of the asymptomatic human carrier state is similarly undefined.
View Article and Find Full Text PDFStable infection of primates with Trypanosoma cruzi I and II.
Parasitology
November 2006
Department of Protozoology, Laboratory of Biology of Tripanosomatid, Institute Oswaldo Cruz - IOC/FIOCRUZ, Av. Brasil 4365, Zip Code 21040-900, Rio de Janeiro, Brazil.
In order to better comprehend the putative association between genotype Trypanosoma cruzi II and primates, an evaluation of the infection in free ranging primates and specimens born in captivity from different geographical areas, the Amazon and the Atlantic forest, was carried out. Seroprevalences of the T. cruzi infection among the primates was similar in both biomes (45.
View Article and Find Full Text PDFAn isoenzyme survey of Trypanosoma brucei s.l. from the Central African subregion: population structure, taxonomic and epidemiological considerations.
Parasitology
June 2004
OCEAC, Laboratoire de Recherche sur les Trypanosomoses, BP 288, Yaoundé, Cameroun.
In order to improve our knowledge about the taxonomic status and the population structure of the causative agent of Human African Trypanosomiasis in the Central African subregion, 169 newly isolated stocks, of which 16 came from pigs, and 5 reference stocks, were characterized by multilocus enzyme electrophoresis, for 17 genetic loci. We identified 22 different isoenzyme profiles or zymodemes, many of which showed limited differences between them. These zymodemes were equated to multilocus genotypes.
View Article and Find Full Text PDFVisceral leishmaniasis in eastern Sudan: parasite identification in humans and dogs; host-parasite relationships.
Microbes Infect
October 2003
Laboratoire de Parasitologie-Mycologie, Centre National de Référence des Leishmania, CHU de Montpellier, 163, rue Auguste-Broussonet, 34090 Montpellier, France.
In 1996, an epidemic outbreak of visceral leishmaniasis (VL) started in Barbar el Fugara, a village in Gedarif State (eastern Sudan). From 1997 to 2000, regular epidemiological studies were carried out in the human population, as well as in mammals and sand flies. In symptomatic patients, 46/69 lymph node, 6/20 post kala-azar dermal leishmaniasis (PKDL) and 1/4 cutaneous cultures in NNN medium were positive.
View Article and Find Full Text PDFAmebic infections due to the Entamoeba histolytica-Entamoeba dispar complex: a study of the incidence in a remote rural area of Ecuador.
Am J Trop Med Hyg
July 2002
Laboratory of Parasitology, Virology Service, Instituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy.
An epidemiologic field study was conducted in the village of Borbòn in Esmeraldas province in northern Ecuador to compare different parasitologic methods in the diagnosis of infection with the Entamoeba histolytica/Entamoeba dispar complex. The results of two stool antigen detection assays (the Prospect Entamoeba histolytica microplate assay and the E. histolytica II assay) were compared with isoenzyme characterization of the amebic isolates.
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