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Mid-Term Outcomes of a Rectangular Stem Design with Metadiaphyseal Fixation and a 135° Neck-Shaft Angle in Reverse Total Shoulder Arthroplasty.
J Clin Med
January 2025
Shoulder and Elbow Surgery, Schulthess Clinic Zürich, 8008 Zürich, Switzerland.
: Classical reverse shoulder arthroplasty (RSA) with a high neck-shaft angle (NSA) of 155° has shown satisfactory outcomes. However, newer RSA designs aim to improve results by modifying the stem design. This study evaluates the 5-year outcomes of a stem design featuring a rectangular metadiaphyseal fixation and a 135° NSA.
View Article and Find Full Text PDFBio-Obturation for Internal Root Resorption in Contralateral Mandibular Molars: A Five-Year Case Study.
Cureus
December 2024
Endodontics, Iranian Center for Endodontic Research, Research Institute of Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran, IRN.
Internal root resorption (IRR) is a rare but complex condition characterized by progressive destruction of the internal dentin walls, typically resulting from chronic pulp inflammation, trauma, or infection. Managing apical IRR, particularly in teeth with extensive apical lesions, presents significant challenges due to the limitations of traditional root canal treatment (RCT) and obturation techniques. This report discusses the nonsurgical management of two contralateral mandibular first molars in a 49-year-old male patient, both exhibiting apical IRR and large endodontic lesions.
View Article and Find Full Text PDFPerforating Internal Root Resorption Sealed with Single-Cone Technique Using Bioceramic Sealer: A Case Report.
Am J Case Rep
January 2025
Department of Restorative Dentistry, College of Dentistry, Umm Al-Qura University, Mekkah, Saudi Arabia.
BACKGROUND Internal root resorption (IRR) is a rare dental condition characterized by the progressive resorption of dentin within the root canal, often resulting from infection, trauma, or orthodontic treatment. When IRR progresses to perforation, it creates a communication pathway with periodontal tissues, necessitating effective endodontic therapy and perforation repair. Bioceramic sealers, known for their biocompatibility and flowability, have emerged as a promising alternative to traditional materials for filling and sealing the root canal system.
View Article and Find Full Text PDFBone regeneration: The influence of composite HA/TCP scaffolds and electrical stimulation on TGF/BMP and RANK/RANKL/OPG pathways.
Injury
January 2025
University Center of Hermínio Ometto Foundation, FHO, Araras 13607-339, SP, Brazil; Division of Dermatology, Department of Internal Medicine, Ribeirao Preto Medical School, University of Sao Paulo, Sao Paulo 05508-060, Brazil; Graduate Program of Orthodontics, University Center of Hermínio Ometto Foundation, FHO, Araras 13607-339, SP, Brazil. Electronic address:
The repair of critical-sized bone defects represents significant clinical challenge. An alternative approach is the use of 3D composite scaffolds to support bone regeneration. Hydroxyapatite (HA) and tri-calcium phosphate (β-TCP), combined with polycaprolactone (PCL), offer promising mechanical resistance and biocompatibility.
View Article and Find Full Text PDFComparative cardiovascular safety of romosozumab versus bisphosphonates in Japanese patients with osteoporosis: a new-user, active comparator design with instrumental variable analyses.
J Bone Miner Res
January 2025
Department of Clinical Epidemiology, Graduate School of Medicine, Fukushima Medical University, Fukushima-city, Fukushima, Japan.
This study analyzed the association of romosozumab, a human monoclonal antibody with bone-forming and bone resorption-inhibiting effects, and bisphosphonates with the development of cardiovascular disease among patients with osteoporosis. A new-user design was employed to address selection bias, and instrumental variable analysis was used to address confounding by indication. Japanese patients aged ≥40 years, diagnosed with osteoporosis or experienced a fragility fracture, were admitted to medical facilities covered by a commercial administrative claims database, and newly prescribed romosozumab or bisphosphonates after the commercialization of romosozumab in Japan (March 4, 2019) were included based on verification of a 180-day washout period.
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