The authors make a synthesis of studies about circadian rhythms in depression and of hypothesis to explain them. They successively study trials on the phases, on the average levels, on the amplitude of rhythms. They conclude the most significant troubles are, shortening of latency on paradoxical sleep for phases, slump of melatonin levels, blunded amplitude of every parameter. Among possible explanations, they present and discuss a trouble of oscillators, a decrease of sensitivity to external synchronizers and a trouble in rhythm coupling.
Download full-text PDF |
Source |
---|
PLoS One
January 2025
Department of Anthropology, University of Toronto Mississauga, Mississauga, Ontario, Canada.
While most studies on Daylight Saving Time (DST) focus on human sleep and well-being, there is a dearth of understanding of how this sudden, human-mitigated change affects the routines of companion animals. The objective of this study was to assess how DST influenced the morning activity pattern of dogs (Canis familiaris). We used accelerometers to record activity in 25 sled dogs and 29 caregiver-companion dog dyads located in or near Ontario, Canada during the Fall Back time shift.
View Article and Find Full Text PDFJ Biol Rhythms
January 2025
Shiu Chien-Gene Lay Department of Bioengineering, University of California, San Diego, La Jolla, California.
The nature of biological research is changing, driven by the emergence of big data, and new computational models to parse out the information therein. Traditional methods remain the core of biological research but are increasingly either augmented or sometimes replaced by emerging data science tools. This presents a profound opportunity for those circadian researchers interested in incorporating big data and related analyses into their plans.
View Article and Find Full Text PDFNat Sci Sleep
January 2025
Department of Urology, Institute of Urology, West China Hospital, Chengdu, People's Republic of China.
Front Med (Lausanne)
January 2025
Department of Ophthalmology, Emory University, Atlanta, GA, United States.
Objective: Myopia prevalence is increasing at alarming rates, yet the underlying mechanistic causes are not understood. Several studies have employed experimental animal models of myopia and transcriptome profiling to identify genes and pathways contributing to myopia. In this study, we determined the retinal transcriptome changes in response to form deprivation in mouse retinas.
View Article and Find Full Text PDFPhotobiomodul Photomed Laser Surg
January 2025
Rubens Siqueira Research Center, São Jose do Rio Preto, Brazil.
Age-related retinal degeneration is associated with mitochondrial dysfunction. Emerging evidence suggests that photobiomodulation therapy (PBMT) using near-infrared light may improve mitochondrial function and visual performance, but its efficacy is critically time-dependent. This article explores how daily biological rhythms and mitochondrial function interact, focusing on the potential of timed PMBT for age-related eye diseases.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!