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Gastric cancer is described as a malignancy occurring in the region between the gastroesophageal junction and the pylorus. According to the histology, majority of gastric cancers are classified as adenocarcinomas. The prevalence of bone metastasis in the general population is 2-3%.

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Article Synopsis
  • Infantile hypertrophic pyloric stenosis (IHPS) is a condition in infants that causes the pylorus to thicken, resulting in gastric outlet obstruction and severe vomiting.
  • This case series discusses two infants with IHPS who displayed metabolic acidosis, rather than the typical metabolic alkalosis usually seen in such cases.
  • The presence of metabolic acidosis suggests there may be different underlying issues in these cases, indicating that diagnosing IHPS may require a more comprehensive approach.
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Article Synopsis
  • Infantile hypertrophic pyloric stenosis (IHPS) is a serious condition in babies where the stomach can't empty properly due to thickened muscles.
  • This study looked at how well treatment works for IHPS in children and what factors affect their recovery.
  • Results showed that a significant number of babies had poor recovery, especially if they waited too long for treatment, had dehydration, or low potassium levels.
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Article Synopsis
  • Ultrasound is the preferred method for diagnosing hypertrophic pyloric stenosis (HPS) in infants, but measurement techniques for the pylorus are inconsistent due to advances in high-frequency transducers.* -
  • A study analyzed ultrasound images from 300 infants, comparing two methods of measuring pyloric muscle thickness, with one method focusing only on the muscularis propria, which showed higher accuracy and sensitivity in diagnosis.* -
  • Results indicated that the muscularis propria was thicker in HPS cases (median of 4.8 mm) compared to normal cases (median of 2.4 mm), and the specific method measuring just this layer had superior diagnostic performance.*
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Nonhypertrophic Pyloric Stenosis in a Neonate: A Rare Presentation.

J Indian Assoc Pediatr Surg

April 2023

Department of Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

Gastric outlet obstruction in neonates due to nonhypertrophic pyloric stenosis (NHPS) is a rare cause. We report the case of a 37-day-old baby boy who presented with complaints of vomiting for the last 2 weeks and an inconsolable cry over the last 2 days. He has been vomiting seven to eight times a day, a few hours after breastfeeding.

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