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Intrauterine Adhesions (IUAs) are characterized by endometrial damage due to endometritis or curettage. Currently, the gold standard for IUA treatment is hysteroscopy, which enables the dissolution of IUA through mechanical or electrosurgical energy. Common strategies to prevent recurrence include the insertion of a balloon catheter or IUD in the uterus.

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High-throughput screening strategies for plastic-depolymerizing enzymes.

Trends Biotechnol

January 2025

Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China; National Technology Innovation Center of Synthetic Biology, Tianjin 300308, China. Electronic address:

A multitude of plastic-depolymerizing microorganisms and enzymes have been discovered in the plastisphere. Identifying and engineering such microbial strains and enzymes necessitate robust and high-throughput screening strategies for developing effective microbial solutions to counter the plastic accumulation problem and decouple the reliance on fossil resources. This review covers new methods and approaches for the effective high-throughput screening of depolymerizing enzymes for various plastics, such as polyethylene terephthalate (PET), polyurethane (PU), and polylactic acid (PLA).

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3D-printed ultra-sensitive strain sensors using biogels prepared from fish gelatin and gellan gum.

Carbohydr Polym

March 2025

Engineering Research Centre of Fujian-Taiwan Special Marine Food Processing and Nutrition (Ministry of Education), Fujian Agriculture and Forestry University, Fuzhou 350002, China; College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, PR China; China-Ireland International Cooperation Centre for Food Material Science and Structural Design, Fuzhou 350002, China. Electronic address:

The long-term sustainable development of flexible electronic devices is limited by a reliance on synthetic polymers that pose dangers for humans and potentially severe ecological problems, as well as a reliance on conventional processing methods. This work aims to exploit 3D printing to develop natural biogels composed of fish gelatin and high acyl gellan gum for use as flexible sensors. The electrical conductivity and mechanical strength were remarkably enhanced through the environmentally friendly enzyme (transglutaminase) cross-linking and non-toxic ethanol modification treatment, which allows the development of 3D printed sensors for temperature, strain, and stress sensors.

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Underwater acoustic propagation is a complex phenomenon in the ocean environment. Traditional methods for calculating acoustic propagation loss rely on solving complex partial differential equations. Deep learning methods, leveraging their robust nonlinear approximation capabilities, can model various physical phenomena effectively, significantly reducing computation time and cost.

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Our article deals with the governance of responsible research and innovation (RRI) and aims to set out a first psychologically grounded decision-theoretic method for the governance of RRI. We approach the governance of RRI as a multicriteria group decision analysis problem of delivering social welfare in an innovation ecosystem. Following such a methodological approach, we develop a psychologically grounded multicriteria group decision analysis method that integrates in its value function the main psychological effects captured in the value function of prospect theory as the main theory of individual decision-making under risk.

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